PMID: 2487080Jan 1, 1989Paper

Distribution of GABA immunoreactivity in the cat retina: a light- and electron-microscopic study

Visual Neuroscience
R G Pourcho, M T Owczarzak

Abstract

The distribution of GABA-like immunoreactivity in the cat retina was studied through the use of preembedding immunocytochemistry for light microscopy and by postembedding immunogold techniques for electron microscopy. Staining was observed in both inner and outer plexiform layers. Approximately 30% of the somata in the amacrine portion of the inner nuclear layer were immunoreactive and included amacrine and interplexiform cells. Horizontal cells and a subpopulation of cone bipolar cells were also stained. In the ganglion cell layer, staining was observed in both small- and medium-sized neurons. GABA-labeled amacrine cells were presynaptic to somata of amacrine cells and to dendrites of amacrine, bipolar, and ganglion cells. Bipolar cells were a major target, receiving more than 60% of all labeled synapses in the inner plexiform layer. Many of these contacts were reciprocal synapses. These findings support a major role for GABA-labeled amacrines in providing feedback inhibition to bipolar cells in the inner retina.

References

Nov 15, 1978·The Journal of Comparative Neurology·R E MarcD M Lam
Jul 1, 1985·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·C Brandon
Jan 1, 1989·The Journal of Comparative Neurology·H Wässle, M H Chun
Jan 1, 1989·The Journal of Comparative Neurology·M H Chun, H Wässle
Jan 2, 1989·Brain Research·D M CarusoR G Pourcho
Jan 26, 1988·Brain Research·B C YuK R Fry
Jun 1, 1986·Experimental Eye Research·J L MosingerK M Studholme
Dec 15, 1987·The Journal of Comparative Neurology·M A FreedP Sterling
Aug 1, 1986·The Journal of Comparative Neurology·E Cohen, P Sterling
May 1, 1985·The Journal of Physiology·J BolzH Wässle
Sep 1, 1985·Journal of Neurophysiology·R Nelson, H Kolb
Sep 20, 1983·The Journal of Comparative Neurology·M A FreedP Sterling
Jan 1, 1983·Vision Research·H Kolb, R Nelson
Jan 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·Y NakamuraP Sterling
Jan 1, 1981·Vision Research·E V Famiglietti

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Citations

Dec 1, 1991·Visual Neuroscience·R G Pourcho, M T Owczarzak
Jul 1, 1991·Visual Neuroscience·H WässleF Müller
Jan 1, 1991·Journal of Pineal Research·I Vigh-TeichmannB Vigh
Jul 20, 1999·The Anatomical Record·M T Owczarzak, R G Pourcho
Sep 8, 1992·The Journal of Comparative Neurology·P R Martin, U Grünert
Jun 19, 1995·The Journal of Comparative Neurology·M Sassoè-PognettoH Wässle
Mar 29, 2002·The Journal of Comparative Neurology·Juan G CuevaNicholas C Brecha
Mar 1, 2005·Visual Neuroscience·Jun ZhangChen-Yu Yang
Apr 8, 2009·The Journal of Comparative Neurology·Luz M DelgadoOliver Schmachtenberg
Mar 18, 2010·The Journal of Comparative Neurology·Chenying GuoNicholas C Brecha
Nov 1, 1991·Visual Neuroscience·J F MullerH Kolb
Apr 1, 1991·Visual Neuroscience·M Yamashita, H Wässle
May 1, 1993·Visual Neuroscience·N VardiP Sterling
Mar 13, 1995·The Journal of Comparative Neurology·C J TylerG J Devries
Jun 1, 1996·Molecular Neurobiology·P D Lukasiewicz
May 1, 1994·Cell and Tissue Research·U GreferathH Wässle
Sep 25, 2002·Physiological Reviews·E A Schwartz
Apr 14, 2010·The European Journal of Neuroscience·Luisa LassováNoga Vardi
Mar 22, 2013·PloS One·Lisa Nivison-SmithMichael Kalloniatis
Jul 22, 1990·The Journal of Comparative Neurology·U Grünert, H Wässle
Jun 22, 1993·The Journal of Comparative Neurology·M H ChunH Wässle
Jan 1, 1996·Visual Neuroscience·L Jojich, R G Pourcho
May 1, 1993·Visual Neuroscience·U GreferathP Seeburg
May 1, 1997·Visual Neuroscience·J ZhangM M Slaughter
Sep 16, 2004·The Journal of Comparative Neurology·Yen-Hong KaoNoga Vardi
Nov 1, 2008·The Journal of Comparative Neurology·Chenying GuoNicholas C Brecha
Sep 1, 1992·Visual Neuroscience·F MüllerH Wässle
Jul 6, 2004·The Journal of Comparative Neurology·Bozena Fyk-KolodziejRoberta G Pourcho

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