Distribution of genes encoding four pathogenicity islands (VPaIs), T6SS, biofilm, and type I pilus in food and clinical strains of Vibrio parahaemolyticus in China

Foodborne Pathogens and Disease
Guoxiang ChaoXiaoqin Qian

Abstract

Vibrio parahaemolyticus is a major cause of foodborne gastroenteritis in China, Japan, and other countries. The pandemic O3:K6 clone, which harbors thermostable direct hemolysin [tdh] gene and toxRS/new gene, is mainly responsible for the foodborne outbreaks after 1995. Previous studies showed that genes in the pathogenicity island-1 (VPaI-1) and VPaI-5 are harbored only by pandemic strains, whereas genes in VPaI-7 and type III secretion system 2 are closely associated with tdh-positive strains of V. parahaemolyticus. In this study, we examined the distribution of genes encoding VPaI-2, VPaI-3, VPaI-4, VPaI-6, type VI secretion systems (T6SS), biofilm, and type I pilus in 71 food and 116 clinical strains of V. parahaemolyticus. The results showed that most of the pandemic strains of V. parahaemolyticus harbored the complete genes of VPaI-2, T6SS, and type I pilus. In contrast, most of the pathogenic strains (harboring tdh gene or TDH-related hemolysin [trh] gene) and nonpathogenic strains (harboring neither tdh gene nor trh gene) contained partial genes of VPaI-2, T6SS, and type I pilus. Genes of VPaI-4 were exclusively present in the pandemic strains. Genes of VPaI-3 were present in most of the pandemic strains and a small per...Continue Reading

References

May 28, 1994·Lancet·M K Waldor, J J Mekalanos
Jan 1, 1995·Annual Review of Microbiology·J W CostertonH M Lappin-Scott
Jun 2, 2000·Journal of Clinical Microbiology·H NasuT Honda
Jun 22, 2000·Proceedings of the National Academy of Sciences of the United States of America·M M BarnhartS J Hultgren
Nov 15, 2000·Emerging Infectious Diseases·N R ChowdhuryG B Nair
Oct 9, 2003·Journal of Clinical Microbiology·Masatoshi OkuraHaruo Watanabe
Feb 3, 2005·Molecular Microbiology·Jodi L Enos-BerlageLinda L McCarter
Jul 8, 2005·Journal of Clinical Microbiology·Masatoshi OkuraHaruo Watanabe
Jan 25, 2006·Proceedings of the National Academy of Sciences of the United States of America·Stefan PukatzkiJohn J Mekalanos
May 5, 2006·BMC Genomics·Catherine C HurleyE Fidelma Boyd
Jan 16, 2007·Clinical Microbiology Reviews·G Balakrish NairDavid A Sack
Feb 16, 2007·Journal of Clinical Microbiology·Carolyn E MeadorGary J Vora
Sep 18, 2007·Proceedings of the National Academy of Sciences of the United States of America·Stefan PukatzkiJohn J Mekalanos
Jul 2, 2008·BMC Microbiology·E Fidelma BoydMichelle A Parent

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Citations

Aug 11, 2010·Archives of Microbiology·Chari Nithya, Shunmugiah Karutha Pandian
Feb 13, 2001·Letters in Applied Microbiology·L CrociL Toti
May 10, 2011·Foodborne Pathogens and Disease·Pendru Raghunath
Apr 12, 2011·Journal of Genetics and Genomics = Yi Chuan Xue Bao·Rongzhi WangShihua Wang
Dec 3, 2014·Letters in Applied Microbiology·Y H TeyH C Wong
Jul 26, 2011·Microbes and Infection·Christopher A BrobergKim Orth
Mar 24, 2015·Frontiers in Microbiology·Rongzhi WangShihua Wang
Feb 18, 2015·Frontiers in Microbiology·Vengadesh LetchumananKok-Gan Chan
Apr 8, 2015·Food Microbiology·Md Furkanur Rahaman MizanSang-Do Ha
Oct 22, 2016·International Journal of Food Microbiology·Xingxing DongJinquan Li
Feb 15, 2011·International Journal of Food Microbiology·Guoxiang ChaoXiaoqin Qian
Mar 12, 2019·Future Microbiology·Dongsheng HanJinming Li
Aug 13, 2011·Physical Biology·Yilin WuMark Alber
Apr 16, 2020·BMC Microbiology·Divya Meparambu PrabhakaranSabu Thomas
Aug 10, 2017·Frontiers in Microbiology·Romilio T EspejoNicolas Plaza

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Methods Mentioned

BETA
electrophoresis

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