Distribution of genes related to antimicrobial resistance in different oral environments: a systematic review

Journal of Endodontics
Ludmila Coutinho MoraesFrancisco Montagner

Abstract

The oral cavity is the main source of microorganisms for odontogenic infections. It is important to perform an extensive analysis regarding the reports on the presence of bacteria that carry resistance genes to antimicrobial agents. The aim of the study was to verify the reports on the distribution of genes associated with resistance to antibiotics prescribed in dentistry in different human oral sites. A systematic review was conducted in electronic databases and gray literature to analyze clinical studies that detected genes of bacterial resistance to antibiotics in saliva, supragingival biofilm, and endodontic infections. Data regarding the research group, geographic location, sample source, number of subjects, methods for sample analysis, the targeted gene groups, and the detection rates were collected. Descriptive data analysis was performed. Preliminary analysis was performed in 152 titles; 50 abstracts were reviewed, and 29 full texts were obtained. Nine articles matched the inclusion criteria (saliva = 2, supragingival biofilm = 1, and endodontic infections = 6). The presence of 33 different targeted genes was evaluated. The most frequently investigated groups of genes were tetracycline and lactamics (tetM, tetQ, tetW, a...Continue Reading

References

Oct 23, 2002·Journal of Clinical Periodontology·M FeresS S Socransky
Feb 27, 2003·Antimicrobial Agents and Chemotherapy·A VilledieuP Mullany
Feb 12, 2004·Oral Microbiology and Immunology·B P F A GomesF J Souza-Filho
May 25, 2004·Antimicrobial Agents and Chemotherapy·A VilledieuP Mullany
Jul 20, 2005·The Journal of Antimicrobial Chemotherapy·Holli LancasterPeter Mullany
Apr 25, 2006·Journal of Endodontics·Matthias Zehnder
Apr 17, 2007·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Lars S W Spångberg
Oct 31, 2007·International Journal of Clinical Pharmacology and Therapeutics·S BaglieF C Groppo
Nov 6, 2007·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Ryusaburo FuruyaMasatoshi Tanaka
Sep 9, 2008·The Journal of Antimicrobial Chemotherapy·Nuria GarcíaAlberto Quesada
Oct 29, 2008·Antimicrobial Agents and Chemotherapy·Philip WarburtonPeter Mullany
May 26, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·José F Siqueira, Isabela N Rôças
Jun 23, 2009·Journal of Clinical Periodontology·Ioannis IoannidisAntonis Konstantinidis
Jul 2, 2009·Journal of Endodontics·Kumar Subramanian, Andre K Mickel
Sep 5, 2009·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Lorna A SevilleAdam P Roberts
Sep 10, 2010·Anaerobe·Gena D TribbleCharles J Smith
Dec 24, 2010·Virulence·Morten O A SommerGautam Dantas
Sep 3, 2011·The Journal of Microbiology·Seon-Mi KimSeok-Woo S Lee
Sep 20, 2011·Journal of Endodontics·Gretchen B JungermannAshraf F Fouad
Dec 4, 2012·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·William G Wade
Apr 25, 2013·Journal of Endodontics·Zhongchun TongYunjing Mu
Jul 16, 2013·Journal of Dentistry·Renata Ximenes LinsRivail Antonio Sergio Fidel
Feb 26, 2014·Journal of Endodontics·Francisco MontagnerBrenda Paula Figueiredo de Almeida Gomes
Apr 5, 2014·Journal of Endodontics·Anibal R DiogenesKenneth M Hargreaves

❮ Previous
Next ❯

Citations

Sep 12, 2015·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Carolin GötzAndreas Kolk
Apr 14, 2016·Journal of Endodontics·Ibrahim Ethem Yaylali, Tayfun Alaçam
Nov 5, 2016·International Journal of Antimicrobial Agents·Pauline M LangFrancisco Montagner
May 18, 2016·Journal of Dental Research·S SukumarC J Adler
Apr 20, 2019·Drug Metabolism Reviews·Paul Andrei TentMihai Juncar
Sep 30, 2020·PloS One·Viviane de Sousa Moreira AlmeidaJoice Neves Reis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.