Distribution of gonococcal lipopolysaccharide biosynthesis genes among strains of Neisseria gonorrhoeae and other neisserial species

Microbial Pathogenesis
D A Palermo-DiltsV L Clark

Abstract

A plasmid, pTME6, containing Neisseria gonorrhoeae lipopolysaccharide biosynthesis genes was used as a probe to analyze DNA from strains of N. gonorrhoeae, N. meningitidis and various commensal Neisseria by Southern blotting. Chromosomal DNA from 26 gonococcal strains probed with 32P-labeled pTME6 produced five different hybridization patterns. No correlation between hybridization pattern and auxotype, serotype, serum sensitivity or SDS-urea-PAGE migration of LPS was observed. DNA from strains of N. meningitidis, N. lactamica and N. cinerea, but not other commensal Neisseria species, hybridized strongly to pTME6.

References

Dec 1, 1975·Canadian Journal of Microbiology·K G JohnsonR R Russel
Feb 1, 1976·Canadian Journal of Microbiology·K G JohnsonI J McDonald
Jul 1, 1988·Reviews of Infectious Diseases·J M GriffissM A Apicella
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Jul 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·D DiMaioT Maniatis

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Citations

May 1, 1993·Molecular Microbiology·B D RobertsonJ P van Putten
Jan 1, 1995·Molecular Microbiology·E T SchwanJ P van Putten

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