Distribution of immunoglobulin determinants on the surface of Xenopus laevis splenic lymphocytes

The Journal of Experimental Zoology
I H Azimi

Abstract

The distribution of surface immunoglobulin (Ig) determinants on Xenopus laevis splenic lymphocytes after combination with divalent rabbit anti-Ig coupled to ferritin was studied. The electron micrographs showed the presence of immune complexes in 67% of lymphocytes treated at 0 degrees C-4 degrees C. The complexes were located all around the membrane and uniformly distributed in a random fashion. The variation of ferritin grain counts on cell sections is such, that the existence of two major subclasses of Ig-positive cells may be suggested. Raising the temperature produced a rapid interiorization of the complexes in vesicles without any previous aggregation to form a "cap" having occurred.

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Citations

Apr 1, 1982·Developmental Biology·I Hadji-AzimiC Thiebaud
Jan 1, 1991·Developmental and Comparative Immunology·C A Varley, J D Horton
Jan 1, 1984·Differentiation; Research in Biological Diversity·J Schwager, I Hadji-Azimi
Aug 14, 1982·British Medical Journal·T J Hamblin

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