PMID: 6402004Feb 1, 1983Paper

Distribution of lead in body fluids after ingestion of soft solder

British Journal of Industrial Medicine
W Manton, C R Malloy

Abstract

Blood, serum, cerebrospinal fluid, and urine obtained from a patient before and after chelation therapy showed that (1) the ratio of Pb in his cerebrospinal fluid to that in his serum varied from 0.4 to 0.9 and was independent of serum Pb concentration; (2) the fraction of Pb in his serum fell linearly with decreasing blood Pb concentration and changed from 1.6% to 0.33% as his blood Pb concentration changed from 116 micrograms/dl (5.6 mumol/l) to 31 micrograms/dl (1.5 mumol/l); and (3) his renal clearance of Pb from serum varied from 5 ml/min to 36 ml/min. This high value was obtained 11 days after chelation and is attributed to large quantities of Sn in his urine promoting the excretion of Pb. Solder was identified in his stool after discovery of radio-opaque material in his bowel. The Pb isotope ratios of the solder were different from those in his urine when he was first admitted, and showed that he had ingested solder when he had returned home on weekend passes.

References

Sep 1, 1979·The Science of the Total Environment·A R Byrne, L Kosta
Feb 1, 1978·British Journal of Industrial Medicine·A CavalleriA Baruffini
Aug 1, 1976·The Journal of Clinical Investigation·M B RabinowitzJ D Kopple
Jul 1, 1977·Archives of Environmental Health·W I Manton
Feb 1, 1971·Toxicology and Applied Pharmacology·P B Hammond
Aug 1, 1981·British Journal of Industrial Medicine·P E deSilva
Jan 1, 1980·Archives of Internal Medicine·W B Bean
Jan 1, 1974·The Journal of Pediatrics·J F RosenE E Trinidad

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Citations

Aug 11, 1984·Lancet·W I MantonJ D Cook
Nov 14, 1997·Pharmacology & Toxicology·I A BergdahlS Skerfving
Nov 1, 1996·Occupational and Environmental Medicine·A SchützS Skerfving
Dec 1, 1993·Environmental Health Perspectives·R W Leggett
Feb 1, 1997·Environmental Health Perspectives·D E FlemingD R Chettle
Dec 23, 1998·Environmental Health Perspectives·P D WhiteR W Elias
Aug 23, 2008·The Science of the Total Environment·Brian Gulson
Feb 5, 1999·Environmental Research·I A BergdahlS Skerfving
Nov 24, 1999·Toxicology and Applied Pharmacology·D E FlemingE J O'Flaherty
Aug 1, 1984·British Journal of Industrial Medicine·W I Manton, J D Cook
Jun 19, 1998·Critical Reviews in Toxicology·E J O'Flaherty
Jan 19, 2006·American Journal of Industrial Medicine·Ingvar A BergdahlStaffan Skerfving
Feb 18, 1998·In Vitro Cellular & Developmental Biology. Animal·M ChowH Rubin
Oct 4, 2019·Scientific Reports·Anca Rădulescu, Steven Lundgren

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