PMID: 9178853May 9, 1997Paper

Distribution of mRNAs for pituitary adenylate cyclase-activating polypeptide (PACAP), PACAP receptor, vasoactive intestinal polypeptide (VIP), and VIP receptors in the rat superior cervical ganglion

Neuroscience Letters
H NogiA Baba

Abstract

The distribution of mRNAs for pituitary adenylate cyclase-activating polypeptide (PACAP), PACAP receptor (PACAP-R), vasoactive intestinal polypeptide (VIP) and two subtypes of VIP receptors (VIP1-R and VIP2-R) was examined by in situ hybridization in the superior cervical ganglion (SCG) of the adult rat. PACAP-R mRNA was expressed intensely in virtually all principal neurons. PACAP mRNA was expressed in approximately half of the principal neurons, where the levels of expression vary extensively. Intense expression of VIP mRNA was observed only in a few principal neurons. Neither VIP1-R mRNA nor VIP2-R mRNA was detected in SCG cells. These findings suggest that PACAP, but not VIP, may function as a paracrine or autocrine regulatory factor through PACAP-R in the principal neurons of the SCG.

References

Jan 1, 1989·Molecular Neurobiology·I Gozes, D E Brenneman
Apr 1, 1994·Trends in Pharmacological Sciences·T Harmar, E Lutz

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Citations

Nov 11, 2003·Life Sciences·Norihito ShintaniAkemichi Baba
Sep 5, 1998·Brain Research. Developmental Brain Research·W J ShewardA J Harmar
Sep 11, 2002·Regulatory Peptides·M Laburthe, A Couvineau
Jun 29, 2002·Molecular and Cellular Endocrinology·Kevin J CummingsNancy M Sherwood
Nov 11, 1999·British Journal of Pharmacology·E M LutzR Mitchell
Jan 4, 2003·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Hitoshi Hashimoto
Oct 6, 2007·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Akemichi Baba
Nov 1, 2001·Proceedings of the National Academy of Sciences of the United States of America·H HashimotoA Baba
Dec 20, 2017·Frontiers in Systems Neuroscience·Beatrice M GirardMargaret A Vizzard
Jul 20, 2018·Journal of Molecular Neuroscience : MN·Thomas J HeppnerMargaret A Vizzard
Apr 19, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Arijit RoyRichard J A Wilson
Feb 22, 2018·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Anne Luise Haulund VollesenMessoud Ashina
Feb 24, 2001·Annals of the New York Academy of Sciences·V MayK M Braas

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