PMID: 7538799Mar 1, 1995Paper

Distribution of neuronal and non-neuronal NADPH diaphorases and nitric oxide synthases in rat uterine horns under different hormonal conditions

Biology of Reproduction
A Mara SuburoM A Gimeno

Abstract

Since pharmacological evidence indicates that nitric oxide (NO) operates in the control of uterine motility, we have studied the distribution of NADPH diaphorase and NO synthases in the rat uterus using histochemical and immunohistochemical methods. Numerous nerve fibers displayed NADPH diaphorase activity and immunoreactivity to antisera raised against neuronal NO synthase. Nerve fibers appeared in all stages of the estrous cycle and also after ovariectomy. NADPH diaphorase activity was also present in endothelia and cells dispersed in the different uterine layers. Most NADPH diaphorase-positive (ND) cells had eosinophilic granules with occasional cells expressing the ED1 macrophage-monocyte marker. Immunoreactivity for an inducible NO synthase was found in a small number of macrophage-like cells without NADPH diaphorase activity. Thus, ND cells may express another NO synthase isoform not detected by the available antisera. In normal cycling rats, ND cells were most abundant during proestrus, and their number further increased after estrogen treatment. ND cells were not observed after ovariectomy but were present after estrogen replacement therapy. ND cells could be involved in the estrogenic control of in vivo and in vitro ut...Continue Reading

Citations

Dec 27, 2011·Archives of Gynecology and Obstetrics·Simone GiuliniAnnibale Volpe
Jan 1, 1996·Pharmacology & Therapeutics·J Norman
Feb 24, 1998·European Journal of Pharmacology·W TakahashiS Ueda
Jul 11, 2001·Urology·A ZiniP N Schlegel
Nov 1, 2003·Reproduction, Fertility, and Development·D OgandoA Franchi
Jun 9, 2009·Reproduction : the Official Journal of the Society for the Study of Fertility·Fuller W BazerGuoyao Wu
Oct 6, 1997·Proceedings of the National Academy of Sciences of the United States of America·M ChaudM F Gimeno
Aug 5, 2008·Reproductive Biology·Aneta Andronowska, Marcin Chruściel
Mar 4, 2008·The American Journal of Pathology·María IribarneAngela M Suburo
Dec 31, 1997·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M A ChaudM F Gimeno
Mar 3, 1998·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M A ChaudM F Gimeno
Apr 3, 1999·Prostaglandins, Leukotrienes, and Essential Fatty Acids·A FranchiM Gimeno
May 23, 2000·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·B GawronskaA J Ziecik
Jul 7, 1997·FEBS Letters·M B HerreroM A Gimeno
Oct 1, 1996·Redox Report : Communications in Free Radical Research·M P ShermanL J Ignarro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
C A WilsonR Machemer
Reproduction : the Official Journal of the Society for the Study of Fertility
M FarinaA M Franchi
Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association
A J ZiecikM Bogacki
© 2021 Meta ULC. All rights reserved