Distribution of the serine-aspartate repeat protein-encoding sdr genes among nasal-carriage and invasive Staphylococcus aureus strains

Journal of Clinical Microbiology
Artur SabatWaleria Hryniewicz

Abstract

The sdr locus was found in all 497 investigated Staphylococcus aureus strains, although in 29 strains it contained only the sdrC gene (sdrD negative, sdrE negative). The sdrC-positive, sdrD-negative, sdrE-negative gene profile was exclusive to methicillin-sensitive S. aureus (MSSA) strains (Fisher's exact test; P = 0.0005) and was not found in the strains collected from bone infections (P = 0.0019). We also found a strong association between the presence of the sdrD gene and methicillin-resistant S. aureus strains (P < 0.0001). Our findings suggest that MSSA strains with the newly uncovered sdrC-positive, sdrD-negative, sdrE-negative gene profile have a substantially decreased potential to establish bone infection.

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Citations

Jun 24, 2010·Antonie van Leeuwenhoek·Izabela SitkiewiczWaleria Hryniewicz
Oct 15, 2009·Future Microbiology·Karthikeyan SivaramanAlexander M Cole
Dec 18, 2010·Future Microbiology·Rasmus V RasmussenNiels E Bruun
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Aug 19, 2015·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Huanle LiuFangyou Yu
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Apr 29, 2014·International Journal of Medical Microbiology : IJMM·Virginia PostT Fintan Moriarty
Oct 16, 2015·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Long M G Bui, Stephen P Kidd
Nov 1, 2016·Infection and Immunity·Fatemeh AskarianMona Johannessen
Apr 17, 2009·Clinical and Vaccine Immunology : CVI·Lena PerssonCecilia Rydén
Nov 19, 2011·The International Journal of Artificial Organs·Carla Renata ArciolaLucio Montanaro
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Apr 18, 2018·BMC Microbiology·Clement AjayiAnne-Merethe Hanssen
Jul 20, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Kavitha Shettigar, Thokur Sreepathy Murali
Nov 30, 2018·Medical Microbiology and Immunology·Vigyasa Singh, Ujjal Jyoti Phukan
Jul 25, 2021·International Journal of Environmental Research and Public Health·Muhammad IdreesAyesha Rahman

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