Distribution, projection and dopaminergic regulation of the neurokinin B mRNA-containing neurons of the rat caudate-putamen.

Neuroscience
J M Burgunder, W S Young

Abstract

Neurons containing transcripts encoding neurokinin B, a member of the tachykinin family, were studied in the rat caudate-putamen using hybridization histochemistry. Neurons containing neurokinin B mRNA were distributed throughout the caudate-putamen, with a slightly higher density in the middle portions as compared with the more rostral and caudal portions. These neurons were either isolated, often located close to neurons devoid of neurokinin B mRNA, or in small clusters of three to 10 cells. A larger group of neurons with neurokinin B mRNA was seen in the ventrolateral caudate-putamen, near the tip of the external capsule. Neurokinin B mRNA was colocalized in neurons with substance P (59% of neurokinin B neurons had substance P mRNA) and with enkephalin mRNA (25% of neurokinin B neurons had enkephalin mRNA). After injections of the fluorescent dye Fluorogold into the globus pallidus and substantia nigra, retrograde axonal transport studies demonstrated neurokinin B mRNA in striatopallidal but not striatonigral projections. The influence of dopaminergic input on the level of neurokinin B mRNA in the caudate-putamen was studied after 6-hydroxydopamine lesions of the substantia nigra/ventral tegmental area. Both the number of ce...Continue Reading

References

Dec 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·W S YoungM R Brann
Feb 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·J E KrauseA D Hershey
Jan 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·B GrimaJ Mallet
Nov 4, 1986·European Journal of Pharmacology·J A AnguloG R Christoph
Jan 1, 1988·Annual Review of Neuroscience·J E Maggio
Sep 1, 1987·Brain Research·T I BonnerW S Young
Oct 1, 1986·Physiology & Behavior·J P Kroon, A L Riley
Apr 8, 1987·The Journal of Comparative Neurology·R E HarlanD W Pfaff
Sep 30, 1971·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J M Kemp, T P Powell
Nov 15, 1983·Biochemical Pharmacology·L J ThalM H Makman
Jun 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·F TangJ P Schwartz
Nov 14, 1984·Biochemical and Biophysical Research Communications·N MinaminoH Matsuo
Jun 15, 1983·Biochemical and Biophysical Research Communications·S L SabolJ S Hong
Jan 1, 1981·Neuroscience·D van der KooyT Hattori
Jun 1, 1981·The Journal of Comparative Neurology·J C FinleyP Petrusz
May 20, 1982·The Journal of Comparative Neurology·C R GerfenH C Fibiger

❮ Previous
Next ❯

Citations

Jun 17, 1998·Molecular Neurobiology·R E Harlan, M M Garcia
Jan 24, 1995·European Journal of Pharmacology·G R SeabrookR G Hill
Jan 1, 1993·Brain Research. Brain Research Reviews·P W Kalivas
Jul 1, 1992·Peptides·I MerchenthalerJ M Conlon
Sep 1, 1994·Progress in Neurobiology·J P Herman, N D Abrous
Aug 1, 1992·Brain Research Bulletin·A W GallagherA M Lynch
Dec 1, 1993·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·E Pérez-NavarroJ Marsal
Jan 1, 1991·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·M KawataY Sano
Sep 24, 2004·Journal of Neurochemistry·Yoshinori MasuoEtsuo Niki
Nov 22, 2007·The European Journal of Neuroscience·Takahiro SonomuraTakeshi Kaneko
Jul 6, 2007·The European Journal of Neuroscience·Yoshinori MasuoEtsuo Niki
Jan 16, 2019·The Journal of Comparative Neurology·Julie M Butler, Karen P Maruska
Mar 22, 1992·The Journal of Comparative Neurology·J MarksteinerJ E Krause

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.