PMID: 2507062Aug 26, 1989Paper

Disturbances of insulin in British Asian and white men surviving myocardial infarction

BMJ : British Medical Journal
L O HughesE B Raftery

Abstract

To examine the role of insulin as a cardiovascular risk factor in British Asian and white men. Case-controlled study of survivors of first myocardial infarction. District general hospital. Consecutive series of 76 white and 74 Asian men who survived first myocardial infarction compared with 58 white and 61 Asian male controls without coronary artery disease who were randomly sampled from the community. More Asians than white subjects had impaired glucose tolerance or overt diabetes as measured by the two hour glucose tolerance test (23/74 (32%) v 11/76 (15%) (p less than 0.001) among patients; 17/61 (28%) v 3/58 (6%) (p less than 0.001) among controls). Insulin and C peptide concentrations were higher in both patient groups than in respective controls (p less than 0.001) and higher in Asian than in white subjects, irrespective of their glucose tolerance. Triglyceride concentrations were higher in patients than in controls (1.92 (SD 1.05) v 1.43 (0.82) mmol/l among Asian men; 1.65 (0.83) v 1.3 (0.61) mmol/l among white subjects; p less than 0.001). Total cholesterol concentrations were lower in both groups of Asians than in respective white subjects (5.78 (0.99) v 6.22 (1.04) mmol/l (p less than 0.01) among patients; 5.54 (1.01)...Continue Reading

References

Nov 1, 1975·Lancet·H T PedoeL McDonald
Jan 1, 1976·The American Journal of Medicine·G M ReavenJ M Olefsky
May 20, 1989·BMJ : British Medical Journal·L O HughesE B Raftery
Feb 11, 1989·Lancet·R C TempleC N Hales
Nov 1, 1988·British Heart Journal·P M McKeigueR A Riemersma
Oct 8, 1988·BMJ : British Medical Journal·P M McKeigue, M G Marmot
Feb 1, 1988·Diabetologia·R J Jarrett
Nov 28, 1986·JAMA : the Journal of the American Medical Association·W P CastelliW B Kannel
Oct 19, 1985·British Medical Journal·H M Mather, H Keen
Jan 1, 1973·Metabolism: Clinical and Experimental·E A Nikkilä, M Kekki
Dec 1, 1971·The American Journal of Medicine·I I Kessler
Aug 22, 1983·The American Journal of Cardiology·W B Kannel

❮ Previous
Next ❯

Citations

Jul 21, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A Misra, L Khurana
Aug 1, 1992·Australian and New Zealand Journal of Medicine·J RajaduraiO Mei Lin
Oct 1, 1991·Diabetic Medicine : a Journal of the British Diabetic Association·K M ShelgikarC S Yajnik
Apr 1, 1993·Journal of Epidemiology and Community Health·T KnightM R Baker
Nov 1, 1994·American Journal of Public Health·C A StuartR M Stahn
Oct 7, 1989·BMJ : British Medical Journal
Nov 4, 1989·BMJ : British Medical Journal·P M McKeigue
Oct 21, 1995·BMJ : British Medical Journal·S GuptaL O Hughes
Mar 8, 2006·The Canadian Journal of Cardiology·Milan Gupta, Stephanie Brister
Jun 1, 1994·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·A LawsG M Reaven
Jan 1, 1997·American Journal of Human Biology : the Official Journal of the Human Biology Council·K Bose, C G N Mascie-Taylor
May 1, 2016·Social History of Medicine : the Journal of the Society for the Social History of Medicine·Martin D Moore
Mar 6, 2007·Annals of Saudi Medicine·S O OlusiT N Sugathan
Apr 9, 2011·Postgraduate Medicine·Steph HemmingsDylan Morrissey

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.