Disturbances of the secretory stage of amelogenesis in fluorosed deer teeth: a scanning electron-microscopic study

Cell and Tissue Research
H Kierdorf, U Kierdorf

Abstract

Structural changes resulting from fluoride-induced disturbances of the secretory stage of amelogenesis were studied in fluorosed dental enamel of ten permanent premolars and molars from roe deer (Capreolus capreolus) and red deer (Cervus elaphus). The fluorosed enamel exhibited surface hypoplasias of different depths and extents and an associated loss of its normal prism/interprism structure. The occurrence of such aprismatic enamel either was restricted to grossly accentuated and hypomineralized incremental (calciotraumatic) bands or affected more extended areas to the bottom of the hypoplastic lesions. The fluoride-induced disturbance of the secretory functions of the cells had thus been either temporary or permanent. Layers of aprismatic enamel were regarded as denoting periods of reduced enamel matrix formation by secretory ameloblasts lacking the distal, i.e., the prism-forming, portions of their Tomes processes. Our observations also indicated that the transition from the presecretory to the secretory stage of amelogenesis could be affected by fluoride, thereby preventing the ameloblasts from achieving their normal secretory function and from establishing fully formed Tomes processes. Aprismatic enamel was formed througho...Continue Reading

Citations

Sep 29, 2009·Journal of Dental Research·A L J J BronckersP K DenBesten
Oct 28, 1997·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·H KierdorfA Boyde
Feb 1, 2011·Archives of Oral Biology·D M LyaruuP K DenBesten
Feb 9, 2010·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Heiko RichterHorst Kierdorf
Sep 3, 2013·American Journal of Physical Anthropology·Daniel H TempleHirofumi Matsumura
Feb 20, 2015·American Journal of Physical Anthropology·Horst KierdorfMark F Skinner
Jul 21, 2015·The Science of the Total Environment·Clare DeathJasmin Hufschmid
Aug 16, 2016·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Horst KierdorfUwe Kierdorf
Mar 11, 2020·American Journal of Physical Anthropology·Brenna R HassettLouise Humphrey
Jun 9, 2020·American Journal of Physical Anthropology·Wendy DirksJoanna M Setchell
Aug 12, 2021·American Journal of Physical Anthropology·Alexandra E Kralick, Kate McGrath

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