Diuretics: an update on the pharmacology and clinical uses

American Journal of Therapeutics
Pramod Reddy, Arshag D Mooradian

Abstract

Diuretics are among the most commonly used drugs. They increase the rate of urine flow and sodium excretion and are used to induce negative fluid and sodium balance in a variety of clinical situations, including hypertension, heart failure, renal failure, nephrotic syndrome, and cirrhosis. It is essential for clinicians to understand the mechanism of action of various diuretics to be able to maximize the efficacy of these agents when used as monotherapy and in combination with agents that have different targets of action in the kidney. The pharmacology of commonly used diuretics and the renal anatomy and physiology relevant to diuretic effects are reviewed.

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Citations

Jun 16, 2010·Clinical Nuclear Medicine·Ba D NguyenOsborn H Howard
Feb 11, 2014·Genomics, Proteomics & Bioinformatics·Xundou LiYouhe Gao
Feb 27, 2010·Journal of Cardiovascular Medicine·Filippo BrandimarteMihai Gheorghiade
Feb 27, 2015·American Journal of Therapeutics·Pramod Reddy, Lori Dupree
Oct 17, 2015·Journal of Nuclear Medicine Technology·Ba D NguyenHoward H Osborn

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