PMID: 9174225Apr 1, 1997Paper

Diurnal plasma vasopressin and urinary output in adolescents with monosymptomatic nocturnal enuresis

Acta Paediatrica
G LäckgrenA Stenberg

Abstract

Plasma arginine vasopressin (AVP) levels, urinary flow and urine osmolality were investigated in a group of adolescents (20 boys and 5 girls), aged 11-21 y, with severe monosymptomatic nocturnal enuresis and a control group of healthy adolescents (16M and 4F) with similar age- and sex-distribution. Half of the control group was investigated twice, with an interval of 6 months. AVP samples were taken every fourth hour in all adolescents and half of the control group were also investigated every second hour to achieve more samples during controlled sleep. After the study the enuretic group were put on long-term oral desmopressin (DDAVP). The difference between day and night values of AVP was significant for both groups, but there was no difference in the day/night ratios of plasma-AVP. All the adolescents produced less urine while asleep, but the controls produced significantly more urine than the enuretics during day. The controls also had a significantly larger nocturnal elevation of urine osmolality than the enuretics, thus a tendency towards polyuria was found. We could not find any significant difference between responders to DDAVP treatment and non-responders in any of the parameters studied. AVP is secreted in a pulsatile ...Continue Reading

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Citations

May 30, 2001·International Journal of Pediatric Otorhinolaryngology·U CinarS Turgut
Nov 2, 2002·BJU International·T NevéusA Stenberg
Oct 9, 2001·Journal of the American Academy of Child and Adolescent Psychiatry·E J Mikkelsen
Sep 23, 2003·The Journal of Urology·Gabriella AcetoPaolo Caione
Oct 29, 1997·Acta Paediatrica·K Hjälmås
Dec 13, 2003·Archives of Disease in Childhood·H Leonard, N Plant
Oct 30, 2010·The Journal of Urology·Carmin M KalorinBarry A Kogan
Dec 17, 2009·The Journal of Urology·Tryggve NeveusUNKNOWN International Children's Continence Society
Jul 31, 2014·The Angle Orthodontist·Nameer Al-TaaiSaad Fakhry
Apr 27, 2004·Journal of Pharmacological Sciences·Shigeki NakamuraToshimi Kambe
Sep 25, 2012·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·J BréaudE Bérard
Dec 19, 2003·European Journal of Clinical Nutrition·F Manz, A Wentz

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