Diurnal variation in microcirculation of ocular fundus and visual field change in normal-tension glaucoma

Eye
T OkunoT Ikeda

Abstract

Diurnal variations in microcirculation of the ocular fundus in normal-tension glaucoma (NTG) were examined to compare with the normal control eyes. The correlation between progression of visual field impairment and diurnal variations in ocular circulation was also studied. The subjects were 12 patients with NTG and 12 normal controls. Blood pressure (BP), intraocular pressure (IOP), ocular perfusion pressure (OPP), and square blur rate (SBR), an index of microcirculation acquired by the laser speckle method, were measured at 9 a.m. (morning), 3 p.m. (afternoon), and 9 p.m. (night). Diurnal variations in SBR were tested using the Friedman test and Wilcoxon signed ranks test. On the other hand, diurnal variations in BP, IOP, and OPP were tested by the analysis of variance. The visual field was evaluated at the same time as determining diurnal variation and again about 9 months later to calculate the change. The correlation between variation ratio in SBR and the change in visual field was examined by simple regression. A significant decrease (P=0.04) was found in SBR at night, as compared with the morning value, in the optic nerve head (ONH) of NTG, although no significant diurnal variations were found in SBR either in the choroid...Continue Reading

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Citations

Jan 1, 2016·Current Opinion in Ophthalmology·Louis R Pasquale
Dec 12, 2012·Survey of Ophthalmology·Luciano QuarantaIvano Riva
Sep 4, 2009·Acta Ophthalmologica·Tetsuya SugiyamaSelim Orgul
Nov 4, 2008·Acta Ophthalmologica·Alexandra LukschLeopold Schmetterer
Nov 19, 2013·Acta Ophthalmologica·Vital P CostaLeopold Schmetterer
Jun 5, 2013·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Jan LestakPavel Rozsival
Sep 14, 2018·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Jan LestakMarketa Stredova
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Jul 9, 2014·Japanese Journal of Ophthalmology·Akira SawadaTetsuya Yamamoto
Sep 21, 2019·Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti·J LeštákL Bartošová
Oct 25, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Hideki ChumanNobuhisa Nao-I
Mar 30, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Alice C Verticchio VercellinFrancesco Oddone

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