Divergence with gene flow in Anopheles funestus from the Sudan Savanna of Burkina Faso, West Africa.

Genetics
A P MichelNora J Besansky

Abstract

Anopheles funestus is a major vector of malaria across Africa. Understanding its complex and nonequilibrium population genetic structure is an important challenge that must be overcome before vector populations can be successfully perturbed for malaria control. Here we examine the role of chromosomal inversions in structuring genetic variation and facilitating divergence in Burkina Faso, West Africa, where two incipient species (chromosomal forms) of A. funestus, defined principally by rearrangements of chromosome 3R, have been hypothesized. Sampling across an approximately 300-km east-west transect largely contained within the Sudan-Savanna ecoclimatic zone, we analyzed chromosomal inversions, 16 microsatellite loci distributed genomewide, and 834 bp of the mtDNA ND5 gene. Both molecular markers revealed high genetic diversity, nearly all of which was accounted for by within-population differences among individuals, owing to recent population expansion. Across the study area there was no correlation between genetic and geographic distance. Significant genetic differentiation found between chromosomal forms on the basis of microsatellites was not genomewide but could be explained by chromosome 3R alone on the basis of loci insi...Continue Reading

References

Jan 1, 1983·Journal of Molecular Evolution·M NeiY Tateno
Jun 1, 1995·Molecular Ecology·D PaetkauC Strobeck
Jul 1, 1993·Parasitology·L C Ranford-CartwrightD Walliker
Mar 31, 1999·Heredity·M C Whitlock, D E McCauley
Jun 3, 2000·Genetics·J K PritchardP Donnelly
Oct 26, 2000·Molecular Ecology·M ClementK A Crandall
Dec 9, 2000·Molecular Biology and Evolution·J P KingR Chakraborty
Jun 14, 2001·Trends in Ecology & Evolution·L H. Rieseberg
Oct 11, 2001·Proceedings of the National Academy of Sciences of the United States of America·M A NoorJ Reiland
Sep 13, 2002·The American Journal of Tropical Medicine and Hygiene·L L KoekemoerM Coetzee
Oct 5, 2002·Science·Mario ColuzziVincenzo Petrarca
Oct 5, 2002·Science·A della TorreM Coluzzi
Nov 26, 2002·Molecular Biology and Evolution·Sebastian E Ramos-Onsins, Julio Rozas
May 2, 2003·The Journal of Heredity·T LehmannW A Hawley
Dec 12, 2003·Bioinformatics·Julio RozasRicardo Rozas
Jan 22, 2004·Nature Reviews. Genetics·Chung-I Wu, Chau-Ti Ting
Feb 6, 2004·The Journal of Heredity·I SharakhovN J Besansky
Jul 10, 2004·Insect Biochemistry and Molecular Biology·M Coetzee, D Fontenille
Aug 5, 2004·Heredity·E E Dakin, J C Avise
Jan 18, 2005·Genetics·Aram D StumpNora J Besansky
Apr 27, 2005·Proceedings of the National Academy of Sciences of the United States of America·Jeffrey L FederMartin Aluja
Apr 27, 2005·Proceedings of the National Academy of Sciences of the United States of America·Francisco J Ayala, Mario Coluzzi
Aug 4, 2005·PLoS Biology·Thomas L TurnerSergey V Nuzhdin
Dec 13, 2005·Medical and Veterinary Entomology·W M GuelbeogoC Costantini

❮ Previous
Next ❯

Citations

Dec 4, 2012·Molecular Biology and Evolution·Marta FarréAurora Ruiz-Herrera
Nov 28, 2006·Malaria Journal·Andrew P MichelNora J Besansky
Feb 25, 2014·Malaria Journal·Wamdaogo M GuelbeogoCarlo Costantini
Jan 16, 2013·Annual Review of Entomology·Maureen Coetzee, Lizette L Koekemoer
Apr 5, 2013·Evolution; International Journal of Organic Evolution·Diego AyalaMark Kirkpatrick
Apr 1, 2015·Evolution; International Journal of Organic Evolution·Konrad LohseWilliam J Etges
Aug 26, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·J R LoaizaJ E Conn
Apr 3, 2016·Molecular Ecology·Amanda M Kenney, Andrea L Sweigart
Sep 21, 2017·PloS One·André Barretto Bruno WilkeMauro Toledo Marrelli
Sep 7, 2016·PloS One·Laura Cristina MultiniMauro Toledo Marrelli
Jan 10, 2020·Parasitology Research·Irina MuntaabskiAlejandra C Scannapieco
Jan 10, 2019·Parasites & Vectors·Edwin O OgolaDavid P Tchouassi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.