Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase

Journal of Structural Biology
Yihong Ye

Abstract

Cdc48/p97, a member of the AAA (ATPase associated with various cellular activities) ATPase family, participates in various cellular pathways including membrane fusion, protein folding/unfolding, proteolysis-dependent transcriptional control, protein degradation, and spindle disassembly. How Cdc48/p97 can perform such diverse functions is unclear, but the recently established connection between components of the ubiquitination system and various p97 activities suggests that these seemingly unrelated processes mediated by Cdc48/p97 may all be governed by ubiquitin.

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Citations

Apr 29, 2008·Cellular and Molecular Life Sciences : CMLS·W Li, Y Ye
May 11, 2011·Cell Research·Harish N Ramanathan, Yihong Ye
May 12, 2010·Immunology and Cell Biology·Sonja I BuschowWillem Stoorvogel
Oct 25, 2011·Nature Cell Biology·Mayura MeerangKristijan Ramadan
Feb 3, 2012·Nature Cell Biology·Hemmo MeyerSebastian Bremer
Oct 21, 2009·Nature Chemical Biology·Erin K SchraderAndreas Matouschek
Jul 14, 2011·Nature Communications·Flávia C NeryXandra O Breakefield
Apr 3, 2012·Nature Structural & Molecular Biology·Willem den BestenRaymond J Deshaies
Aug 30, 2008·Proceedings of the National Academy of Sciences of the United States of America·Julien MouyssetThorsten Hoppe
Jan 24, 2009·Proceedings of the National Academy of Sciences of the United States of America·Qiuyan WangYihong Ye
Oct 22, 2011·The Journal of Biological Chemistry·Valentina A ShchedrinaVadim N Gladyshev
Jan 22, 2013·The Journal of Biological Chemistry·Philipp KirchnerHemmo Meyer
Jan 18, 2008·The Journal of Biological Chemistry·Qiuyan WangYihong Ye
Mar 12, 2008·The Journal of Biological Chemistry·Louise C BriggsPaul S Freemont
May 30, 2008·The Journal of Biological Chemistry·Jihui RenRobert C Piper
Apr 11, 2009·The Journal of Biological Chemistry·Sven M AlbertsDieter H Wolf
Oct 23, 2013·The Journal of Cell Biology·Albert Lu, Suzanne R Pfeffer
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May 25, 2013·Cell & Bioscience·Harish N RamanathanYihong Ye
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Jul 31, 2013·Drug Design, Development and Therapy·Niraj M Sakhrani, Harish Padh
Apr 5, 2014·Nature Structural & Molecular Biology·John C Christianson, Yihong Ye
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Sep 25, 2007·Proceedings of the National Academy of Sciences of the United States of America·Daqi TuAxel T Brunger
May 17, 2014·DNA and Cell Biology·Ting Zhang, Yihong Ye

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