PMID: 6407007May 1, 1983Paper

Diversity and joining segments of mouse immunoglobulin heavy chain genes are closely linked and in the same orientation: implications for the joining mechanism

Proceedings of the National Academy of Sciences of the United States of America
C Wood, S Tonegawa

Abstract

We have mapped 12 diversity (D) gene segments of mouse Ig heavy chains between 80 and 1 kilobases 5' to the four joining (JH) gene segments by molecular analysis of DNA clones isolated from recombinant phage and cosmid libraries. All identified D and JH segments are in the same 5'-3' orientation. The significance of these findings with respect to the joining mechanism for Ig gene segments is discussed.

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Citations

Jan 1, 1992·Mammalian Genome : Official Journal of the International Mammalian Genome Society·P D'Eustachio
Jan 1, 1992·Immunogenetics·T C Tobin-Janzen, J E Womack
Apr 1, 1988·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·S Tonegawa
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Oct 1, 1989·Immunology Today·U KrawinkelT Blankenstein
Aug 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·D L Wood, C Coleclough
Apr 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·P P ChenD A Carson
Nov 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·H W SchroederR M Perlmutter
Apr 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·R K Gill, S Christakos
Jul 1, 1988·The Journal of Experimental Medicine·G D YancopoulosF W Alt
Nov 1, 1990·The Journal of Experimental Medicine·A J Feeney
Jan 1, 1988·Annals of the New York Academy of Sciences·P J GearhartU V Malipiero
Feb 1, 1988·Bioscience Reports·S Tonegawa
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Nov 1, 1986·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·J E BermanF W Alt
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Feb 19, 2021·Nature·Leonid A Mirny
Mar 27, 2021·Nature Reviews. Molecular Cell Biology·Iain F Davidson, Jan-Michael Peters

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