Diversity of cytochrome P450 genes in the mosquito, Anopheles albimanus

Biochemical and Biophysical Research Communications
J A ScottR Feyereisen

Abstract

Degenerate oligonucleotide primers were designed for conserved regions of cytochrome P450 proteins of the CYP4 family and were used to amplify cDNA or genomic DNA from different strains of the New World malaria vector, Anopheles albimanus (Weidemann). The PCR products were cloned, sequenced and compared to each other and to members of the P450 family CYP4. Seventeen new P450 genes were identified in five CYP4 subfamilies. Five of the ten PCR products of genomic DNA were shown to contain a short (60-79 bp) intron at the same position as introns in the Drosophila CYP4D2 and CYP4E1 genes.

Citations

Feb 17, 1999·Annual Review of Entomology·R Feyereisen
Apr 13, 2000·Annual Review of Entomology·J Hemingway, H Ranson
Dec 24, 2002·Journal of Medical Entomology·Mark Q Benedict, Cristina S Rafferty
Nov 21, 2007·Marine Environmental Research·Anne JørgensenOle Andersen
Jun 14, 2006·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Kim F RewitzOle Andersen
Jun 12, 1996·Molecular & General Genetics : MGG·B C DunkovR Feyereisen
Aug 18, 2004·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·K F RewitzO Andersen
Jan 1, 2008·Archives of Insect Biochemistry and Physiology·Shaoming HuangL B Brattsten
Oct 5, 2002·Science·Hilary RansonRené Feyereisen
Apr 14, 2005·Journal of the American Mosquito Control Association·Prinyada RodpraditPornpimol Rongnoparut
Aug 5, 2000·Archives of Insect Biochemistry and Physiology·J P DavidJ C Meyran
Oct 26, 1999·Biochemical and Biophysical Research Communications·C Dauphin-VillemantR Lafont
Jul 18, 1997·Biochemical and Biophysical Research Communications·P H FalckhJ P Ahokas
Mar 1, 1997·General Pharmacology·A E Simpson
Oct 8, 1999·Insect Biochemistry and Molecular Biology·J G Scott
Feb 11, 1999·Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology·D J BrownR J Van Beneden

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