Apr 11, 2020

Measuring antimicrobial use on dairy farms: a longitudinal method comparison study

BioRxiv : the Preprint Server for Biology
Gwen M ReesK. K. Reyher


Antimicrobial use on UK dairy farms is measured for surveillance purposes and utilizes veterinary sales data as a proxy for use. Two other methods of recording use have been used commonly on-farm: medicine waste bins and farm medicine records. However, none of these methods have been validated to measure antimicrobial use. The objectives of this research are to assess agreement between the 3 most common methods for measuring on-farm antimicrobial use with a pre-determined 'gold standard' measure. Antimicrobial use was measured prospectively on 26 UK dairy farms using medicine waste bins into which participants placed all discarded medicine packaging for a 12-month period. At the end of 12 months, farm medicine records and veterinary sales data were obtained retrospectively for participating farms. The systematic difference between the mean on-farm antimicrobial use measured by each of the 3 methods with a gold standard measure was investigated using one-way repeated measures ANOVAs. Reliability and clinical relevance of the agreement between each pair of methods was quantified using the concordance correlation coefficient and the Bland-Altman method, respectively. Veterinary sales data shows excellent reliability for all forms ...Continue Reading

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Stokesia (plankton genus)
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