Diversity of Staphylococcus pseudintermedius in carriage sites and skin lesions of dogs with superficial bacterial folliculitis: potential implications for diagnostic testing and therapy

Veterinary Dermatology
Rikke LarsenPeter Damborg

Abstract

Staphylococcus pseudintermedius is genotypically diverse within the canine population and multiple strains may colonize individual dogs at any given time. If multiple strains with distinct antimicrobial resistance profiles are present in superficial bacterial folliculitis (SBF), sampling a single skin lesion for culture and antimicrobial susceptibility testing (AST) might be inadequate to select effective therapy. To investigate S. pseudintermedius diversity in carriage sites and lesions of dogs with SBF. Fourteen dogs with SBF. Staphylococcus pseudintermedius isolates obtained from perineum, gingiva and four to six skin lesions per dog were subjected to pulsed-field gel electrophoresis (PFGE) and AST to assess diversity between lesions. For two dogs, 14-16 isolates per lesion were included in the analysis to assess diversity within lesions. Analysis of one isolate per lesion revealed one to four strains displaying unique PFGE profiles, and up to three unique antimicrobial resistance (AMR) profiles for each dog. Multiple pustules from the same dog always harboured the same strain, whereas papules, crusts and collarettes did not. Up to four strains with distinct AMR profiles were isolated from the same lesion in two dogs. In 12 ...Continue Reading

References

May 12, 2010·Veterinary Dermatology·Jennifer FazakerleyTim Nuttall
Mar 12, 2011·The Journal of Antimicrobial Chemotherapy·Martina EscherGaia Scavia
Apr 21, 2012·Veterinary Dermatology·Jeanette Bannoehr, Luca Guardabassi
Feb 28, 2015·The Veterinary Clinics of North America. Small Animal Practice·Luca Guardabassi, John F Prescott
Jan 31, 2017·Veterinary Dermatology·Luca GuardabassiUNKNOWN ESCMID Study Group for Veterinary Microbiology

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