Diverting ileostomy in laparoscopic rectal cancer surgery: high price of protection

Surgical Endoscopy
Peter IhnátPavel Zonča

Abstract

Anastomotic leakage presents the most feared complication after low anterior resection (LAR). A proximal diversion of the gastrointestinal tract is recommended to avoid septic complications of anastomotic leakage. The aim of the present study was to evaluate the benefits and risks of diverting ileostomy (DI) created during laparoscopic LAR because of low rectal cancer. This was a retrospective clinical cohort study conducted to assess outcomes of laparoscopic LAR with/without DI in a single institution within a 6-year period. In total, 151 patients were enrolled in the study (73 patients without DI, 78 patients with DI). There were no significant differences between both groups regarding demographic and clinical features. Overall 30-day morbidity rates were significantly lower in patients without DI (23.3 vs. 42.3 %, P = 0.013). Symptomatic anastomotic leakage occurred more frequently in patients without DI (9.6 vs. 2.5 %, P = 0.090); surgical intervention was needed in 6.8 % of patients without DI. Post-operative hospital stay was significantly longer in the group of patients with DI (11.3 ± 8.5 vs. 8.1 ± 6.9 days, P = 0.013). Stoma-related complications occurred in 42 of 78 (53.8 %) patients with DI; some patients had more th...Continue Reading

Associated Clinical Trials

References

Apr 8, 1998·The British Journal of Surgery·E RullierM Parneix
Dec 22, 1998·Diseases of the Colon and Rectum·P C Shellito
Sep 28, 2002·Diseases of the Colon and Rectum·Frank MaruschHans Lippert
Sep 28, 2004·The British Journal of Surgery·N S AbrahamM J Solomon
Nov 4, 2004·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·P MatthiessenR Sjödahl
Apr 30, 2005·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·I RobertsonA Macdonald
Jul 6, 2005·The British Journal of Surgery·I GastingerUNKNOWN Working Group 'Colon/Rectum Carcinoma'
Nov 3, 2005·Annals of the Royal College of Surgeons of England·D A HarrisM E Foster
Feb 18, 2009·International Journal of Colorectal Disease·Andre ChowSanjay Purkayastha
Apr 17, 2010·Annals of Surgery·Bogdan C PaunW Donald Buie
Sep 28, 2010·The British Journal of Surgery·P NastroP J Lunniss
Dec 18, 2010·European Journal of Medical Research·T HerzogWaldemar Uhl
May 12, 2012·International Journal of Colorectal Disease·Oscar ÅkessonPamela Buchwald
Sep 4, 2012·The Journal of Surgical Research·Bodil GesslerEva Angenete
Apr 17, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·S NurkinH I Tiszenkel
May 24, 2013·Annals of Coloproctology·Seok In SeoJin Cheon Kim
Sep 24, 2013·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·H FloodeenP Matthiessen
Oct 3, 2013·Annals of Surgical Oncology·Uma R PhatakGeorge J Chang
Jul 6, 2014·Digestive Surgery·Peter IhnátPavel Zonča
Jan 31, 2015·Langenbeck's Archives of Surgery·Mark H HannaAlessio Pigazzi
Feb 19, 2015·Annals of Surgical Oncology·Heleen S SnijdersJan Willem T Dekker
Jun 10, 2015·International Journal of Colorectal Disease·M F SierR J Oostenbroek

❮ Previous
Next ❯

Citations

Sep 18, 2016·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Sami A ChadiSteven D Wexner
Dec 17, 2016·Journal of Medical Systems·Jana NowakováVáclav Snášel
Nov 10, 2018·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·H JutestenM L Lydrup
Feb 18, 2020·Asian Journal of Endoscopic Surgery·Yoshiaki KitaShoji Natsugoe
Apr 21, 2017·The Journal of Trauma and Acute Care Surgery·Paula FerradaUNKNOWN EAST Multi-Institutional Trials Committee
Mar 14, 2018·International Journal of Colorectal Disease·Ri Na YooHyungJin Kim
Jun 30, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Nicholas P McKennaElizabeth B Habermann
Feb 5, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Chen LiuIan Bissett
Oct 17, 2020·International Journal of Colorectal Disease·Nasir Zaheer AhmadAmjad Parvaiz
Mar 31, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Joseph P BoruckiAdam T Stearns
Jun 15, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A K WarpsUNKNOWN Dutch ColoRectal Audit group
Jul 6, 2021·Scandinavian Journal of Gastroenterology·Kevin AfshariAbbas Chabok
Sep 25, 2021·International Journal of Colorectal Disease·A K WarpsR A E M Tollenaar
Sep 26, 2021·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Bolckmans RoelWolthuis Albert
Sep 21, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Irene VogelJulie A Cornish
Nov 5, 2021·World Journal of Surgical Oncology·Yu MuJiannan Li
Jan 15, 2022·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·W LiangL Kang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.