DNA array technology and diagnostic microbiology

Expert Review of Molecular Diagnostics
R M AnthonyG L French

Abstract

Near instantaneous detection of pathogens from clinical material, combined with simultaneous prediction of their antimicrobial resistance profiles, would revolutionize the impact of microbiology on the management of infection. Array-based assays allow a range of characteristics to be rapidly and simultaneously determined. At present these systems have found their primary role as research tools for the monitoring of mRNA expression in the form of DNA microarrays or 'chips'. As fabrication costs reduce and validated targeted arrays are developed, it is inevitable they will be used for more routine applications. Microfluidics offers the exciting possibility of combining purification, amplification and detection in a single disposable device; microarrays are particularly suitable for use within these systems. Arrays will become an important tool for clinical diagnostics.

References

Oct 1, 1995·Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·H De BeenhouwerF Portaels
Jul 15, 1997·Nucleic Acids Research·J WeilerJ D Hoheisel
Feb 6, 1998·Analytical Biochemistry·T LivacheG Mathis
Apr 15, 2000·Science·J FritzJ K Gimzewski
Jun 24, 2000·Nature·D J Lockhart, E A Winzeler
Jul 25, 2000·Analytical Chemistry·J KhandurinaJ M Ramsey
Feb 7, 2001·Applied and Environmental Microbiology·S G BavykinA D Mirzabekov
Mar 7, 2001·Journal of Clinical Microbiology·L WestinJ P O'Connell

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Citations

Apr 21, 2009·Analytical and Bioanalytical Chemistry·Jan Weile, Cornelius Knabbe
Oct 6, 2009·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Kenzo UchidaHisatoshi Baba
Jun 18, 2002·European Journal of Internal Medicine·Olivier Cussenot
Feb 4, 2003·American Journal of Pharmacogenomics : Genomics-related Research in Drug Development and Clinical Practice·Alessandro Serretti, Paola Artioli
Sep 13, 2005·Journal of Microbiological Methods·T J BrownF A Drobniewski
Aug 27, 2005·Clinica Chimica Acta; International Journal of Clinical Chemistry·David ZhangBingjiao Yin
May 14, 2004·Journal of Biomolecular Screening·Oren BeskeSimon Goldbard
Aug 9, 2002·Tropical Medicine & International Health : TM & IH·Henk D F H Schallig, Linda Oskam
Jan 17, 2003·Expert Review of Molecular Diagnostics·Alex van Belkum, Alain Troesch
Jan 17, 2003·Expert Review of Molecular Diagnostics·Gabor L Igloi
Jan 17, 2003·Expert Review of Molecular Diagnostics·Thean Yen Tan
Apr 19, 2005·Expert Review of Molecular Diagnostics·Bruce H Davis
Dec 26, 2006·Expert Review of Molecular Diagnostics·Michael M LingPeter Lea
Mar 22, 2003·Expert Review of Molecular Diagnostics·Vadim V Demidov
Mar 22, 2003·Expert Review of Molecular Diagnostics·David Y Zhang, Bin Liu
Nov 12, 2003·American Journal of Clinical Pathology·M Ali Ansari-LariMichael J Borowitz

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