DNA-based applications in nanobiotechnology.

Journal of Biomedicine & Biotechnology
Khalid M Abu-SalahSalman A Alrokayan

Abstract

Biological molecules such as deoxyribonucleic acid (DNA) have shown great potential in fabrication and construction of nanostructures and devices. The very properties that make DNA so effective as genetic material also make it a very suitable molecule for programmed self-assembly. The use of DNA to assemble metals or semiconducting particles has been extended to construct metallic nanowires and functionalized nanotubes. This paper highlights some important aspects of conjugating the unique physical properties of dots or wires with the remarkable recognition capabilities of DNA which could lead to miniaturizing biological electronics and optical devices, including biosensors and probes. Attempts to use DNA-based nanocarriers for gene delivery are discussed. In addition, the ecological advantages and risks of nanotechnology including DNA-based nanobiotechnology are evaluated.

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Citations

Oct 12, 2012·Analytical and Bioanalytical Chemistry·Caterina FedeLucia Celotti
Jan 1, 2010·Sensors·Anees A AnsariAbdullah S Aldwayyan
Jun 24, 2015·Sensors·Khalid M Abu-SalahAnees A Ansari
Jul 30, 2015·Organic & Biomolecular Chemistry·Hagar Tigger-Zaborov, Galia Maayan
May 18, 2021·Asian Journal of Pharmaceutical Sciences·Athirah Bakhtiar, Ezharul Hoque Chowdhury

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Methods Mentioned

BETA
chip
biosensors
biosensing
transmission electron microscopy
fluorescence imaging
surface plasmon resonance
biosensor
transfection
Fluorescence
antisense oligonucleotides

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