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DNA cleavage induced by oxyl radicals generated in the photosensitized decomposition of fatty ester hydroperoxides derived from oleic and linoleic acid

Archives of Biochemistry and Biophysics

Feb 4, 1998

W AdamC R Saha-Möller

Abstract

The xanthone-sensitized photodecomposition of the fatty ester hydroperoxides 1 and 2 in the presence of pBR 322 DNA was investigated as a chemical model system to assess whether this process may cause DNA damage through oxyl radicals. Unequivocally, oxyl radicals are formed in the xanth...read more

Mentioned in this Paper

Hydrogen Peroxide
Linoleic Acid
Lipid Peroxides
Lipids
Mannitol
DNA Cleavage
Oleic Acids
Peroxides
Photochemistry
Radicals (chemistry)
Paper Details
References

DNA cleavage induced by oxyl radicals generated in the photosensitized decomposition of fatty ester hydroperoxides derived from oleic and linoleic acid

Archives of Biochemistry and Biophysics

Feb 4, 1998

W AdamC R Saha-Möller

PMID: 9448713

DOI: 10.1006/abbi.1997.0353

Abstract

The xanthone-sensitized photodecomposition of the fatty ester hydroperoxides 1 and 2 in the presence of pBR 322 DNA was investigated as a chemical model system to assess whether this process may cause DNA damage through oxyl radicals. Unequivocally, oxyl radicals are formed in the xanth...read more

Mentioned in this Paper

Hydrogen Peroxide
Linoleic Acid
Lipid Peroxides
Lipids
Mannitol
DNA Cleavage
Oleic Acids
Peroxides
Photochemistry
Radicals (chemistry)

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Paper Details
References
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