DNA-mediated exciton coupling and electron transfer between donor and acceptor stilbenes separated by a variable number of base pairs

Journal of the American Chemical Society
Frederick D LewisM R Wasielewski

Abstract

The synthesis, steady-state spectroscopy, and transient absorption spectroscopy of DNA conjugates possessing both stilbene electron donor and electron acceptor chromophores are described. These conjugates are proposed to form nicked DNA dumbbell structures in which a stilbenedicarboxamide acceptor and stilbenediether donor are separated by variable numbers of A-T or G-C base pairs. The nick is located either adjacent to one of the chromophores or between two of the bases. Thermal dissociation profiles indicate that stable structures are formed possessing as few as two A-T base pairs. Circular dichroism (CD) spectra in the base pair region are characteristic of B-DNA duplex structures, whereas CD spectra at longer wavelengths display two bands attributed to exciton coupling between the two stilbenes. The sign and intensity of these bands are dependent upon both the distance between the chromophores and the dihedral angle between their transition dipoles [Deltaepsilon approximately Rda(-2) sin(2theta)]. Pulsed laser excitation of the stilbenediamide results in creation of the acceptor-donor radical ion pair, which decays via charge recombination. The dynamics of charge separation and charge recombination display an exponential di...Continue Reading

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Citations

Jul 7, 2011·Journal of the American Chemical Society·Arun K ThazhathveetilFrederick D Lewis
Sep 11, 2012·Journal of the American Chemical Society·Arun K ThazhathveetilFrederick D Lewis
May 15, 2013·Journal of the American Chemical Society·Yunqi YanDavid S Ginger
Jun 30, 2009·Journal of the American Chemical Society·Josh Vura-WeisFrederick D Lewis
Oct 21, 2005·Organic Letters·Young Jun SeoByeang Hyean Kim
Sep 30, 2005·Chemical Communications : Chem Comm·Yan ZhengFrederick D Lewis
Jul 5, 2007·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Dimitra MarkovitsiFrancis Talbot
Oct 10, 2014·Photochemistry and Photobiology·Almaz S JalilovFrederick D Lewis
Oct 22, 2016·Nature Chemistry·Nicolas RenaudFerdinand C Grozema
Sep 13, 2006·The Journal of Chemical Physics·Eric R Bittner
Jan 18, 2017·Journal of the American Chemical Society·Arun K ThazhathveetilFrederick D Lewis
Jan 5, 2006·Organic & Biomolecular Chemistry·Ligang ZhangFrederick D Lewis
Mar 31, 2015·Journal of the American Chemical Society·Ryan M YoungMichael R Wasielewski
Oct 8, 2015·Faraday Discussions·Arunoday P N SinghFrederick D Lewis
May 12, 2006·Organic & Biomolecular Chemistry·Milan BalazNina Berova
Oct 31, 2006·Angewandte Chemie·Frederick D LewisMichael R Wasielewski
Apr 10, 2008·Angewandte Chemie·Frederick D LewisMichael R Wasielewski
Jan 10, 2009·Chemistry : a European Journal·Silvia AlesiGiovanna Barbarella
Jan 26, 2007·Organic & Biomolecular Chemistry·Ligang ZhangFrederick D Lewis
Nov 30, 2013·Physical Chemistry Chemical Physics : PCCP·Antonino ArrigoSebastiano Campagna
Feb 9, 2007·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Satoru NakajimaShozo Tero-Kubota
Oct 8, 2004·Photochemistry and Photobiology·Frederick D Lewis
Nov 17, 2009·Inorganic Chemistry·F Albert CottonCarlos A Murillo
Jun 14, 2008·The Journal of Physical Chemistry. B·Khatcharin Siriwong, Alexander A Voityuk
Mar 28, 2007·The Journal of Physical Chemistry. B·D BalamuruganAlexander L Burin
Feb 26, 2009·The Journal of Physical Chemistry. a·Raanan CarmieliMichael R Wasielewski
May 14, 2010·Inorganic Chemistry·Matthew B CoppockMary Elizabeth Williams
May 13, 2011·Journal of the American Chemical Society·Starla D Glover, Clifford P Kubiak
Oct 10, 2014·Journal of the American Chemical Society·Ashutosh Kumar MishraFrederick D Lewis
Aug 3, 2018·Accounts of Chemical Research·Frederick D LewisMichael R Wasielewski
Aug 15, 2012·The Journal of Physical Chemistry. B·Sameer PatwardhanFerdinand C Grozema
Jun 10, 2014·The Journal of Physical Chemistry. a·Arun Kalliat ThazhathveetilFrederick D Lewis
Jul 1, 2014·The Journal of Physical Chemistry. B·Xing YinDavid H Waldeck
Aug 3, 2017·Journal of the American Chemical Society·Kristen E BrownMichael R Wasielewski

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