PMID: 9551175Jan 1, 1997Paper

DNA methylation and genome imprinting in the zebrafish, Danio rerio: some evolutionary ramifications

Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire
R A McGowan, C C Martin

Abstract

Although methylation has been recognized as an important component in a number of developmental processes in mammals, in zebrafish almost nothing is known about this epigenetic modification. This is despite the fact that the zebrafish is becoming increasingly popular as a developmental model system. The little work that has been done on methylation and development in fish concerns genomic imprinting. In mammals, imprinting results in an inability to reproduce parthenogenetically because a genetic contribution from both parents is necessary to successfully complete development. However, this is not true of zebrafish, and a number of the theories that have been presented to explain the evolution of imprinting are not consistent with imprinting in these fish. A new model is presented that discusses some of the potential evolutionary ramifications of methylation and imprinting and that leads to the suggestion that imprinting may actually be a simple genetic mechanism to enhance the efficient evolution of both individual genetic loci and combinations of loci with related functions, without risking the population as a whole. This model can accommodate all of the information known about imprinting, including its broad phylogenetic ran...Continue Reading

Citations

Jun 22, 2000·Molecular Reproduction and Development·L B KoskiR J Etches
Jun 10, 2009·Chromosoma·Ozren Bogdanović, Gert Jan C Veenstra
Aug 12, 2008·Genetica·Hamish G Spencer
Jul 24, 2013·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Xiefan FangKristine L Willett
Dec 10, 2002·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Ronald B WalterChristi A Walter
Aug 12, 2005·Cytogenetic and Genome Research·J F McDonaldA J Matzke
Jun 10, 2005·Genetics·Ky Sha, Andrew Fire
Jan 23, 1999·Current Opinion in Genetics & Development·L D Hurst, G T McVean
Oct 30, 2013·Biological Reviews of the Cambridge Philosophical Society·Luke Holman, Hanna Kokko

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