DNA methylation in early development

Molecular Reproduction and Development
Theresa M Geiman, Kathrin Muegge

Abstract

Development from separate parental germ cells through fertilization and proceeding to a fully functioning adult animal occurs through an intricate program of transcriptional and chromatin changes. Epigenetic alterations such as DNA methylation are an important part of this process. This review looks at the role of DNA methylation in early embryonic development, as well as how this epigenetic mark affects stem cell differentiation and tissue-specific gene expression in somatic cells.

References

Sep 1, 1992·Human Molecular Genetics·J S SutcliffeS T Warren
Oct 1, 1995·Genes & Development·C BeardR Jaenisch
Sep 1, 1994·Human Genetics·D F SmeetsG Hamers
Jan 11, 1996·Nature·G D PennyN Brockdorff
Jan 1, 1995·Human Molecular Genetics·R J GibbonsD R Higgs
Aug 15, 1996·Genes & Development·B Panning, R Jaenisch
Nov 14, 1997·Nature Genetics·A Olek, J Walter
Jul 25, 1998·Genes & Development·N RougierE Viegas-Péquignot
Oct 6, 1999·The Journal of Cell Biology·M C Cardoso, H Leonhardt
Dec 10, 1999·Proceedings of the National Academy of Sciences of the United States of America·R S HansenS M Gartler
Dec 10, 1999·Cell·A P Bird, A P Wolffe
Feb 17, 2000·Nature·W MayerT Haaf
Apr 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·T M Geiman, K Muegge
May 10, 2000·Current Biology : CB·J OswaldJ Walter
May 29, 2000·Current Opinion in Genetics & Development·I B Van den Veyver, H Y Zoghbi
Oct 14, 2000·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·W MayerT Haaf
Mar 17, 2001·Nature Reviews. Genetics·W Reik, J Walter
Apr 28, 2001·Biochimica Et Biophysica Acta·T M GeimanK Muegge
Oct 18, 2001·Molecular and Cellular Biology·D L Carlone, D G Skalnik
Nov 17, 2001·Genes & Development·K DennisK Muegge
Nov 22, 2001·Proceedings of the National Academy of Sciences of the United States of America·W DeanW Reik
Nov 24, 2001·Science·D Bourc'hisT H Bestor
Mar 9, 2002·Molecular and Cellular Biology·Detlev BiniszkiewiczRudolf Jaenisch
May 22, 2002·Nature Genetics·Bernard W FutscherFrederick E Domann
Sep 28, 2002·Mechanisms of Development·Daisuke WatanabeShoji Tajima
Dec 14, 2002·Proceedings of the National Academy of Sciences of the United States of America·Frederic ChedinChih-Lin Hsieh
Jan 21, 2003·Genesis : the Journal of Genetics and Development·Natasha LaneWolf Reik
May 17, 2003·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Alessandra RenieriFranca Cambi
Jun 5, 2003·BMC Molecular Biology·Jean B MargotHeinrich Leonhardt
Feb 6, 2004·The Journal of Biological Chemistry·Naoko HattoriKunio Shiota
Apr 24, 2004·The Journal of Biological Chemistry·Isao SuetakeShoji Tajima

❮ Previous
Next ❯

Citations

Jul 13, 2011·Journal of Inherited Metabolic Disease·Nuria Carrillo-Carrasco, Charles P Venditti
Jun 4, 2013·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Nosheen MalikRuqian Zhao
Oct 5, 2010·Genes & Development·Eric L Fritz, F Nina Papavasiliou
Jan 30, 2010·Journal of Applied Physiology·Adam G EverttsBenjamin A Garcia
Jun 19, 2013·BMC Genomics·Béatrice de MonteraClaude Robert
Apr 3, 2012·Environmental Health Perspectives·Molly L KileDavid C Christiani
Nov 10, 2010·PloS One·Molly L KileDavid C Christiani
May 17, 2013·International Journal of Biological Sciences·Anna MontesanoIleana Terruzzi
Apr 16, 2014·BMC Medical Genomics·Hong-Dan WangBo-Feng Zhu
Mar 15, 2014·International Journal of Oncology·Shota UekusaHiroki Nagase
Sep 25, 2014·BioMed Research International·Bhupender SharmaShamsher S Kanwar
May 3, 2011·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Michelle L North, Anne K Ellis
Oct 14, 2014·Mutation Research. Genetic Toxicology and Environmental Mutagenesis·Shuang YeChunlin Shao
Aug 1, 2012·Epigenetics : Official Journal of the DNA Methylation Society·Fumihiko MaekawaKeiko Nohara
May 23, 2013·International Journal of Radiation Biology·Shuang YeChunlin Shao
Jul 24, 2013·Journal of Neurochemistry·Cihangir YandimRichard Festenstein
Jul 10, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Cristiana Libardi Miranda FurtadoClaudia Pessoa
Nov 5, 2014·Genome Biology and Evolution·Nilmini HettiarachchiNaruya Saitou
Aug 6, 2015·The British Journal of Nutrition·Elizabeth A DeVilbissBrian K Lee
Dec 30, 2016·Journal of Human Kinetics·Paweł CięszczykMyosotis Massidda
Nov 7, 2016·Molecular Genetics and Genomics : MGG·Farzeen Kader, Meenu Ghai
Nov 5, 2016·Expert Opinion on Therapeutic Patents·H S FernandesN M F S A Cerqueira
Nov 5, 2019·Frontiers in Genetics·Sára Sándor, Enikő Kubinyi
Oct 6, 2020·Autism Research : Official Journal of the International Society for Autism Research·Caichen ZhongKristen Lyall
Oct 7, 2017·Epigenetics & Chromatin·Vincenzo Cavalieri, Giovanni Spinelli
Aug 26, 2018·The Journal of Dermatology·Sebastian YuHsin-Su Yu
Dec 6, 2018·Advanced Healthcare Materials·Midori MaedaShuichi Takayama
Sep 26, 2020·Neuroscience and Biobehavioral Reviews·Stefania CiafrèMarco Fiore

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.