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DNA methylation modulates transcription factor occupancy chiefly at sites of high intrinsic cell-type variability

bioRxiv

Feb 27, 2014

Matthew T MauranoJohn A Stamatoyannopoulos

Abstract

The nuclear genome of every cell harbors millions of unoccupied transcription factor (TF) recognition sequences that harbor methylated cytosines. Although DNA methylation is commonly invoked as a repressive mechanism, the extent to which it actively silences specific TF occupancy sites ...read more

Mentioned in this Paper

DNMT1 gene
CTCF gene
Internal
Site
Ctcf Pathway
Methylation
Transcription Factor
DNA Methylation
Modulated
DNA Methylation [PE]
13
26
Paper Details
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DNA methylation modulates transcription factor occupancy chiefly at sites of high intrinsic cell-type variability

bioRxiv

Feb 27, 2014

Matthew T MauranoJohn A Stamatoyannopoulos

PMID: 990003061

DOI: 10.1101/003061

Abstract

The nuclear genome of every cell harbors millions of unoccupied transcription factor (TF) recognition sequences that harbor methylated cytosines. Although DNA methylation is commonly invoked as a repressive mechanism, the extent to which it actively silences specific TF occupancy sites ...read more

Mentioned in this Paper

DNMT1 gene
CTCF gene
Internal
Site
Ctcf Pathway
Methylation
Transcription Factor
DNA Methylation
Modulated
DNA Methylation [PE]
13
26

Similar Papers Found In These Feeds

Paper Details
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