DNA Motif Databases and Their Uses

Current Protocols in Bioinformatics
Gary D Stormo

Abstract

Transcription factors (TFs) recognize and bind to specific DNA sequences. The specificity of a TF is usually represented as a position weight matrix (PWM). Several databases of DNA motifs exist and are used in biological research to address important biological questions. This overview describes PWMs and some of the most commonly used motif databases, as well as a few of their common applications.

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Citations

Feb 15, 2017·Proceedings of the National Academy of Sciences of the United States of America·Niyati JainBlanton S Tolbert
Dec 19, 2017·Bioinformatics·Aziz Khan, Anthony Mathelier
Dec 19, 2015·Current Protocols in Bioinformatics·Annelien VerfaillieStein Aerts
Nov 21, 2015·Nucleic Acids Research·Ivan V KulakovskiyVsevolod J Makeev
Jun 8, 2017·Frontiers in Genetics·Lily Li, Zeba Wunderlich
Nov 9, 2019·Nucleic Acids Research·Oriol FornesAnthony Mathelier
Aug 6, 2021·Briefings in Bioinformatics·Stefano CastellanaTommaso Mazza
Jul 28, 2021·Proteomics·Paula WeidemüllerJudith B Zaugg

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