DNA origami: a history and current perspective

Current Opinion in Chemical Biology
Jeanette NangreaveHao Yan

Abstract

Researchers have been using DNA for the rational design and construction of nanoscale objects for nearly 30 years. Recently, 'scaffolded DNA origami' has emerged as one of the most promising assembly techniques in DNA nanotechnology with a broad range of applications. In the past two years alone, DNA origami has been used to assemble water-soluble probe tiles for label-free RNA hybridization, to study single-molecule chemical reactions, to probe distance-dependent multivalent ligand-protein binding effects, and to organize a variety of relevant molecules including proteins, carbon nanotubes, and metal nanoparticles. This review will recount the origin, evolution, and current status of this extremely versatile assembly technique.

References

Apr 6, 1993·Biochemistry·T J Fu, N C Seeman
Jul 1, 1998·Annual Review of Biophysics and Biomolecular Structure·N C Seeman
Jun 25, 2003·Proceedings of the National Academy of Sciences of the United States of America·Hao YanJohn H Reif
Feb 13, 2004·Nature·William M ShihGerald F Joyce
Dec 8, 2005·Journal of the American Chemical Society·Yan LiuHao Yan
Mar 17, 2006·Nature·Paul W K Rothemund
Jul 13, 2006·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Chenxiang LinHao Yan
Sep 21, 2007·Proceedings of the National Academy of Sciences of the United States of America·Rebecca Schulman, Erik Winfree
May 8, 2009·Nano Letters·Yonggang KeHao Yan
May 14, 2009·Small·Aren E GerdonH Tom Soh
May 19, 2009·Nanotechnology·Anton KuzykPäivi Törmä
Jun 30, 2009·Chembiochem : a European Journal of Chemical Biology·Akinori KuzuyaMakoto Komiyama
Jul 9, 2009·Chemical Communications : Chem Comm·Akinori Kuzuya, Makoto Komiyama
Jul 22, 2009·Biophysical Journal·Jeanette NangreaveYan Liu
Sep 8, 2009·Nature Nanotechnology·Ryan J KershnerGregory M Wallraff
Oct 8, 2009·Journal of the American Chemical Society·Yonggang KeHao Yan
Nov 10, 2009·Nature Nanotechnology·Hareem T MauneErik Winfree
Mar 2, 2010·Nature Nanotechnology·Niels V VoigtKurt Vesterager Gothelf

❮ Previous
Next ❯

Citations

Jan 12, 2012·Chemical Reviews·Ofer I Wilner, Itamar Willner
Mar 4, 2011·Nano Letters·Qian MeiDeirdre Meldrum
Aug 25, 2011·Nature Communications·Akinori KuzuyaMakoto Komiyama
Mar 2, 2011·Nature Methods·Carlos Ernesto CastroHendrik Dietz
Nov 8, 2011·Nature Nanotechnology·Andre V PinheiroHao Yan
Apr 13, 2011·Chemical Communications : Chem Comm·Omid Khakshoor, Eric T Kool
Nov 17, 2012·Nucleic Acids Research·Chenxiang LinWilliam M Shih
May 23, 2012·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Ludovico CademartiriGeoffrey A Ozin
Nov 20, 2012·Science·Michael S Strano
Feb 11, 2016·ACS Nano·J Alexander Liddle, Gregg M Gallatin
Mar 13, 2013·Current Opinion in Biotechnology·Fuan WangItamar Willner
Nov 13, 2012·Trends in Cell Biology·Yamuna Krishnan, Mark Bathe
Mar 8, 2016·ACS Nano·Xiaoxi ZhuangXing-Jie Liang
Dec 2, 2011·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Nicole MichelottiNils G Walter
Nov 5, 2013·Methods : a Companion to Methods in Enzymology·Tien Anh NgoTakashi Morii
Nov 14, 2014·Critical Reviews in Analytical Chemistry·Elisabeth P GatesAdam T Woolley
Jun 27, 2015·PloS One·Alexandra Peacock-VilladaMara Prentiss
Apr 28, 2016·Biotechnology Journal·Mari TakaharaNoriho Kamiya
Mar 3, 2017·Nano Letters·Heidi-Kristin WalterHans-Achim Wagenknecht
Feb 9, 2017·ChemistryOpen·Alessandro AngelinChristof M Niemeyer
Feb 28, 2015·Chemical Communications : Chem Comm·Richie E Kohman, Xue Han
Apr 11, 2015·Organic & Biomolecular Chemistry·Josipa BrglezChristof M Niemeyer
Jul 29, 2017·Nano Letters·Dongfang WangPhilip Tinnefeld
Jul 12, 2017·Angewandte Chemie·Kersten S RabeChristof M Niemeyer
Jan 6, 2016·Chemical Communications : Chem Comm·Nuli XieKemin Wang
Apr 9, 2015·Chemical Communications : Chem Comm·Lin NiuDehai Liang
Mar 20, 2015·Dalton Transactions : an International Journal of Inorganic Chemistry·Philipp Ensslen, Hans-Achim Wagenknecht
Jun 7, 2018·Chemical Communications : Chem Comm·Kazunori Matsuura
Jul 12, 2018·Nanoscale·Janane F RahbaniHanadi F Sleiman
Jan 4, 2012·Chemistry, an Asian Journal·Yulia V Gerasimova, Dmitry M Kolpashchikov
Sep 9, 2011·Small·Barbara Saccà, Christof M Niemeyer
Jul 5, 2012·Small·Barbara SaccàChristof M Niemeyer
Jun 24, 2014·Chembiochem : a European Journal of Chemical Biology·Maria TintoréCarmen Fábrega
Aug 1, 2014·Angewandte Chemie·Finn LohmannMichael Famulok
Apr 11, 2018·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Ying LiuRebecca E Taylor
Jun 26, 2018·Angewandte Chemie·Lauren L K TaylorMaarten M J Smulders
Jan 5, 2019·Chemistry : a European Journal·Teresa BurgahnChristof M Niemeyer
Feb 16, 2019·Advanced Materials·Yong Hu, Christof M Niemeyer
Dec 3, 2016·Proceedings. Biological Sciences·Andrew N RadfordFilippo Aureli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.