DNA Origami and G-Quadruplex Hybrid Complexes Induce Size Control of Single-Walled Carbon Nanotubes via Biological Activation

ACS Nano
Hiroshi Atsumi, Angela M Belcher

Abstract

DNA self-assembly has enabled the programmable fabrication of nanoarchitectures, and these nanoarchitectures combined with nanomaterials have provided several applications. Here, we develop an approach for cutting single-walled carbon nanotubes (SWNTs) of predetermined lengths, using DNA origami and G-quadruplex hybrid complexes. This approach is based on features of DNA: (1) wrapping SWNTs with DNA to improve the dispersibility of SWNTs in water; (2) using G-quadruplex DNA to confine hemin in close proximity to SWNTs and enhance the biological activation of hydrogen peroxide by hemin; and (3) forming DNA origami platforms to allow for the precise placement of G-quadruplexes, enabling size control. These integrated features of DNA allow for temporally efficient cutting of SWNTs into desired lengths, thus expanding the availability of SWNTs for applications in the fields of nanoelectronics, nanomedicine, nanomaterials, and quantum physics, as well as in fundamental studies.

References

Sep 30, 1998·Chemistry & Biology·P TravascioD Sen
Jan 24, 2003·Nature·Nadrian C Seeman
Nov 26, 2004·Journal of the American Chemical Society·Ming Zheng, Bruce A Diner
Mar 17, 2006·Nature·Paul W K Rothemund
Aug 4, 2007·Journal of the American Chemical Society·Jeffrey A FaganErik K Hobbie
Oct 18, 2007·Journal of the American Chemical Society·Faisal A Aldaye, Hanadi F Sleiman
Apr 23, 2008·Journal of the American Chemical Society·Xiaoming SunHongjie Dai
Jun 4, 2008·Physical Review Letters·Alexander HögeleAtac Imamoğlu
Jul 26, 2008·Nature Nanotechnology·B C SatishkumarStephen K Doorn
May 9, 2009·Nature·Ebbe S AndersenJørgen Kjems
May 22, 2009·Nature·Shawn M DouglasWilliam M Shih
Nov 7, 2009·Journal of the American Chemical Society·Brett L AllenAlexander Star
Nov 10, 2009·Nature Nanotechnology·Hareem T MauneErik Winfree
Mar 2, 2010·Nature Nanotechnology·Niels V VoigtKurt Vesterager Gothelf
Oct 30, 2010·Journal of the American Chemical Society·Yuta SannoheHiroshi Sugiyama
Nov 26, 2010·Nature Nanotechnology·Aaron D Franklin, Zhihong Chen
Jul 23, 2011·Nature Chemistry·Sungwook Woo, Paul W K Rothemund
Feb 22, 2012·Science·Shawn M DouglasGeorge M Church
May 23, 2012·Angewandte Chemie·Hiroshi AbeYoshihiro Ito
Oct 4, 2012·Nature Reviews. Genetics·Matthew L BochmanVirginia A Zakian
Nov 20, 2012·Science·Martin LangeckerFriedrich C Simmel
Dec 5, 2012·Organic & Biomolecular Chemistry·Zhao ZhaoHao Yan
Feb 7, 2013·Journal of the American Chemical Society·Anshuman MangalumMichael L Norton
Sep 18, 2014·Nature Communications·Neelkanth M BardhanAngela M Belcher
Oct 11, 2014·Science·Wei SunPeng Yin
Dec 9, 2017·Nature·Florian PraetoriusHendrik Dietz
Dec 9, 2017·Nature·Klaus F WagenbauerHendrik Dietz

❮ Previous
Next ❯

Citations

Oct 12, 2018·Nanoscale·Rajendra Kurapati, Alberto Bianco
Nov 27, 2020·Nature Communications·Robert NißlerSebastian Kruss
Jun 5, 2021·Advanced Healthcare Materials·Luyao ShenYonggang Ke
Jan 4, 2019·Chemical Reviews·Jean-Louis Mergny, Dipankar Sen
Feb 5, 2019·Chemical Reviews·Mikael Madsen, Kurt V Gothelf
Feb 26, 2020·Nano Letters·Honghong WuJuan Pablo Giraldo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved