DNA polyhedra with T-linkage

ACS Nano
Xiang LiChengde Mao

Abstract

This paper reports a strategy for DNA self-assembly. Cross-over-based DNA nanomotifs are held together by T-junctions instead of commonly used sticky-end cohesion. We have demonstrated this strategy by assembling a DNA tetrahedron, an octahedron, and an icosahedron. The resulting DNA polyhedra contain out-pointing, short DNA hairpin spikes. These hairpins are well-structured relative to the polyhedra core and provide potential locations for introduction of functional chemicals such as proteins and gold nanoparticles. The T-linked DNA polyhedra have been characterized by polyacrylamide gel electrophoresis, atomic force microscopy, and dynamic light scattering.

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Citations

Apr 4, 2014·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Kohta MohriYoshinobu Takakura
Oct 13, 2015·Angewandte Chemie·Hua ZuoChengde Mao
Jan 31, 2015·Nature Communications·Jinwen YuChengde Mao
Apr 29, 2016·Soft Matter·Wei PanDehai Liang
May 18, 2016·Chembiochem : a European Journal of Chemical Biology·Wolfgang Pfeifer, Barbara Saccà
Oct 4, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Cheng TianChengde Mao
Oct 12, 2016·Journal of the American Chemical Society·Pengfei WangChengde Mao
Dec 8, 2016·Organic & Biomolecular Chemistry·Weili ShenNadrian C Seeman
Jan 5, 2017·ACS Nano·Cheng TianHaitao Liu
Feb 27, 2013·Chemical Communications : Chem Comm·Zhou NieChengde Mao
Mar 13, 2015·Physical Review Letters·Flavio Romano, Francesco Sciortino
Sep 23, 2020·Chembiochem : a European Journal of Chemical Biology·Dhiraj BhatiaLudger Johannes
Feb 23, 2019·ACS Applied Materials & Interfaces·Longfei LiuChengde Mao
Aug 30, 2018·ACS Applied Materials & Interfaces·Chao XingHuang-Hao Yang

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