DNA polymorphisms of apolipoprotein B in the population of Senegal

Annals of Human Genetics
M ChauffertF Trivin

Abstract

Three apolipoprotein B (apoB) genetic polymorphisms, the XbaI, MspI and EcoRI restriction fragment length polymorphisms (RFLPs), were analysed for 221 individuals in Senegal by polymerase chain reaction. Allelic frequency determination revealed that this population has 0.79 XbaI- (X-), 0.96 MspI+ (M+), and 0.89 EcoRI+ (E+). Major genotypes were X-/X- (0.62), M+/M+ (0.92) and E+/E+ (0.80). The XbaI allele frequency is different (p < 10(-9)) from that in Caucasians (0.47) and from that in Mongoloids (0.98). Significant differences between Senegalese and Caucasians, and between Senegalese and Mongoloids were also observed for the EcoRI and MspI alleles of the apoB genes.

Citations

Oct 30, 2016·The Open AIDS Journal·Vitaris KodogoExnevia Gomo
Nov 16, 2004·Journal of Clinical Laboratory Analysis·Tatsuya SakumaMario H Hirata

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