PMID: 9552385Jan 1, 1996Paper

DNA replication licensing factor

Progress in Cell Cycle Research
J P Chong, J Julian Blow

Abstract

DNA Replication Licensing Factor (RLF) is an essential activity required to restrict the duplication of genomic DNA to precisely once per cell cycle. Recent fractionation of RLF activity from Xenopus egg extracts has resulted in the identification of two essential components, RLF-B and RLF-M. RLF-M has been purified to homogeneity and has been shown to consist of a complex of proteins in the MCM/P1 family. RLF-B is still unidentified, but possible candidates for this activity have been identified in yeast. Elucidation of the RLF mechanism will provide important insights into the way that chromosome replication is controlled.

Citations

Jan 11, 2000·Journal of Cellular Biochemistry·H L Ford, A B Pardee
Dec 1, 2009·Microbiology and Molecular Biology Reviews : MMBR·Matthew L Bochman, Anthony Schwacha
Apr 17, 2016·In Vitro Cellular & Developmental Biology. Animal·Huansheng YangYulong Yin
Mar 4, 2020·Genes·Robert M Brosh, Steven W Matson
Jul 25, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·A SalvettiR Batistoni
Mar 13, 2014·BMC Pharmacology & Toxicology·Naissan HussainzadaJonathan D Stallings
Jun 13, 2015·Molecular Cancer Research : MCR·Victoria L BryantMark G Alexandrow

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