journal cover

DNA sequencing with chain-terminating inhibitors

Proceedings of the National Academy of Sciences of the United States of America

Dec 1, 1977

F SangerA R Coulson

PMID: 271968

Abstract

A new method for determining nucleotide sequences in DNA is described. It is similar to the "plus and minus" method [Sanger, F. & Coulson, A. R. (1975) J. Mol. Biol. 94, 441-448] but makes use of the 2',3'-dideoxy and arabinonucleoside analogues of the normal deoxynucleoside triphosphat...read more

Mentioned in this Paper

Arabinonucleosides
DNA, Viral
Bacteriophages
DNA Polymerase I
Sequence Determinations, DNA
Base Sequence
DNA Restriction Enzymes
Deoxyribonucleotides
Coliphages
DNA-Directed DNA Polymerase
87
1
3
6861
12
1
Paper Details
References
  • References11
  • Citations31992
12
  • References11
  • Citations31992
12345...

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DNA sequencing with chain-terminating inhibitors

Proceedings of the National Academy of Sciences of the United States of America

Dec 1, 1977

F SangerA R Coulson

PMID: 271968

DOI:

Abstract

A new method for determining nucleotide sequences in DNA is described. It is similar to the "plus and minus" method [Sanger, F. & Coulson, A. R. (1975) J. Mol. Biol. 94, 441-448] but makes use of the 2',3'-dideoxy and arabinonucleoside analogues of the normal deoxynucleoside triphosphat...read more

Mentioned in this Paper

Arabinonucleosides
DNA, Viral
Bacteriophages
DNA Polymerase I
Sequence Determinations, DNA
Base Sequence
DNA Restriction Enzymes
Deoxyribonucleotides
Coliphages
DNA-Directed DNA Polymerase
87
1
3
6861
12
1

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Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.

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Nucleic Acids Research

A comprehensive set of sequence analysis programs for the VAX

Nucleic Acids ResearchJanuary 11, 1984
J DevereuxO Smithies
Proceedings of the National Academy of Sciences of the United States of America

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination

Proceedings of the National Academy of Sciences of the United States of AmericaJuly 1, 1983
M D BigginG F Hong
Paper Details
References
  • References11
  • Citations31992
12
  • References11
  • Citations31992
12345...
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