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DNA sequencing with stacked nanopores and exonuclease: A simulation-based analysis

Electrophoresis

Jun 18, 2016

Gopalan Sampath

Abstract

Experiments have shown that DNA can be sequenced using an electrolytic cell with a nanopore and an exonuclease enzyme in the cis chamber that cleaves the leading mononucleotide in a strand of DNA. The base therein can be identified with an accuracy of 80-90% by the level of the current ...read more

Mentioned in this Paper

Cleaved
Genus Cis
Flavin Mononucleotide
Nucleic Acid Sequencing
USP4
Cleaved Cell
Sequencing
Nuclear Translocation
Pore
Sequence Determinations, DNA
Paper Details
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DNA sequencing with stacked nanopores and exonuclease: A simulation-based analysis

Electrophoresis

Jun 18, 2016

Gopalan Sampath

PMID: 27313188

DOI: 10.1002/elps.201600049

Abstract

Experiments have shown that DNA can be sequenced using an electrolytic cell with a nanopore and an exonuclease enzyme in the cis chamber that cleaves the leading mononucleotide in a strand of DNA. The base therein can be identified with an accuracy of 80-90% by the level of the current ...read more

Mentioned in this Paper

Cleaved
Genus Cis
Flavin Mononucleotide
Nucleic Acid Sequencing
USP4
Cleaved Cell
Sequencing
Nuclear Translocation
Pore
Sequence Determinations, DNA

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Chromosomal Translocation

Chromosomal Translocation occur when regions on two chromosomes breaks and swaps places or when a region is attached to another chromosome. Discover the latest research on Chromosomal Translocation here.

Nanopore Sequencing

Nanopore sequencing is a third generation pproach used in the sequencing of biopolymers- specifically, polynucleotides in the form of DNA or RNA. Discover the latest research on nanopore sequencing.

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DNA sequencing with nanopores

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Paper Details
References
  • References6
  • Citations
1
  • References6
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
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