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DNA sequencing with stacked nanopores and exonuclease: a simulation-based analysis

bioRxiv

Jan 27, 2016

G Sampath

Abstract

Experiments (Clarke et al., Nat. Nanotech., 2009, 4, 265-270) have shown that DNA could be sequenced using a nanopore-based electrolytic cell in which an exonuclease enzyme in the cis chamber cleaves the leading base of a strand of DNA. The base is identified (with a reported accuracy t...read more

Mentioned in this Paper

Genus Cis
USP4
Nuclear Translocation
Pore
Sequence Determinations, DNA
Exonuclease
Intracellular Translocation
Biochemical Turnover
Simulation
Analysis
6
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DNA sequencing with stacked nanopores and exonuclease: a simulation-based analysis

bioRxiv

Jan 27, 2016

G Sampath

PMID: 990038034

DOI: 10.1101/038034

Abstract

Experiments (Clarke et al., Nat. Nanotech., 2009, 4, 265-270) have shown that DNA could be sequenced using a nanopore-based electrolytic cell in which an exonuclease enzyme in the cis chamber cleaves the leading base of a strand of DNA. The base is identified (with a reported accuracy t...read more

Mentioned in this Paper

Genus Cis
USP4
Nuclear Translocation
Pore
Sequence Determinations, DNA
Exonuclease
Intracellular Translocation
Biochemical Turnover
Simulation
Analysis
6

Similar Papers Found In These Feeds

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Genomic Techniques (Preprints)

Recent developments in genomics and further development of advanced post-genomic technologies, it will be possible to apply a more holistic analysis to genomic analysis. Discover the latest preprints in genomic techniques.

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