DNA-templated in situ growth of AgNPs on SWNTs: a new approach for highly sensitive SERS assay of microRNA

Chemical Communications : Chem Comm
Jing ZhengRonghua Yang

Abstract

In this communication, we find that the single-walled carbon nanotubes (SWNTs) can demonstrate an excellent ssDNA concentration-dependent surface enhanced Raman scattering (SERS) effect after the decoration of DNA-templated in situ grown AgNPs on the surface. Inspired by this, the SWNT@AgNPs hybrid nanocomposite was employed to achieve microRNA detection which is also sensitive to crude extraction from human breast cancer cells and even patient tissues before and after chemotherapy.

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Citations

Aug 18, 2018·Biotechnology Journal·Jaewook LeeEnoch Y Park
Oct 25, 2017·Analytical Methods : Advancing Methods and Applications·Hao LiangXiaobing Zhang
Oct 21, 2018·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Jiang OuyangYou-Nian Liu
Sep 19, 2018·Nanomaterials·Min JiaHongyan Zhang

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