Do adolescents with a severe idiopathic scoliosis have higher locations of the conus medullaris than healthy adolescents?

Journal of Pediatric Orthopedics
Xu SunYong Qiu

Abstract

Based on the "uncoupled neuro-osseous growth" theory, the hypothesized etiology of adolescent idiopathic scoliosis (AIS), a shorter spinal cord or a higher conus location, could be found in AIS patients. However, there are no case-control studies with large samples regarding the conus position in AIS patients. This study is performed to determine the positions of the conus medullaris in AIS patients with a large curve magnitude when compared with healthy adolescents and to investigate the relationships of the conus locations with patients' age, sex, curve magnitude, and curve pattern. Two hundred forty AIS patients with a Cobb angle greater than 40 degree were included in this study, and 120 age-matched healthy adolescents were recruited to serve as controls. Both AIS patients and healthy controls displayed normal on neurological examinations. On sagittal magnetic resonance images of the spine in both groups, the position on the conus medullaris relative to lumbar vertebrae and intervertebral disk space was measured according to a standard method. There was no significant difference in the distributions of the positions of the conus medullaris in AIS patients and healthy controls (P = 0.448). In both groups, the mean position o...Continue Reading

References

May 1, 1968·Acta Radiologica: Diagnosis·M Roth
Jan 25, 2002·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·R W Porter
Mar 19, 2003·Spine·Cristina M JusticeAlexander F Wilson
Jan 10, 2004·Pediatric Rehabilitation·R G Burwell
Jan 10, 2004·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Thomas G LoweP H Dangerfield
Aug 11, 2004·Spine·Alain MoreauGuy Grimard
Oct 14, 2004·Spine·Bradford C BennettKevin P Granata
Dec 16, 2006·Pediatrics International : Official Journal of the Japan Pediatric Society·Feng ZhuJack Chun-Yiu Cheng

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Citations

Jun 3, 2016·Scoliosis and Spinal Disorders·R Geoffrey BurwellAlan Moulton
Sep 5, 2013·Orthopaedic Surgery·Li-feng LaoJian-xiong Shen
Feb 6, 2018·The Open Orthopaedics Journal·Maja Fadzan, Josette Bettany-Saltikov
Sep 9, 2015·Neurosurgery·Amir KershenovichJoseph H Lock

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