PMID: 2095738Jan 1, 1990Paper

Do all melanomas come from "moles"? A study of the histological association between melanocytic naevi and melanoma

The Australasian Journal of Dermatology
R MarksG Mason

Abstract

Histological examination of 1101 melanomas (990 superficial spreading and 111 nodular melanomas) from 1098 people revealed that 23.3% showed an associated melanocytic naevus. Of these, 56.5% were classified histologically as common acquired, 37.7% as dysplastic and 5.8% as congenital. Of the superficial spreading melanomas, 25.7% showed an associated naevus. By contrast, only 2.7% of nodular melanomas showed histological evidence of a coexisting naevus. When the superficial spreading melanomas were analysed by level, the presence of a naevus varied from 31.3% of level I melanomas to 21.3% of level IV melanomas. When thickness was measured, an associated naevus was found in 27.0% of superficial spreading melanomas less than 1.0 mm thick, and 14.8% of melanomas with a thickness of 1.0 mm or greater. These data suggest that most melanomas do not arise in pre-existing naevi, and accordingly public educational programs for the early detection of melanoma should focus on looking for changes in previously normal skin as well as in pre-existing moles.

References

Jun 1, 1979·Journal of Cutaneous Pathology·S Lopansri, M C Mihm
Dec 1, 1979·The American Journal of Surgical Pathology·R W Sagebiel
Feb 1, 1989·Cancer·W StolzO Braun-Falco
Apr 13, 1984·JAMA : the Journal of the American Medical Association
Jan 1, 1981·Journal of Cancer Research and Clinical Oncology·E Ehring, H Loth

❮ Previous
Next ❯

Citations

Jul 27, 2010·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Agnessa Gadeliya GoodsonDouglas Grossman
Jul 28, 2011·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Agnessa Gadeliya GoodsonDouglas Grossman
Oct 29, 2004·Journal of Clinical Pathology·K S CulpepperP H McKee
Jun 7, 2013·Anais Brasileiros De Dermatologia·Nurimar Conceição Fernandes
Mar 10, 2004·Lancet·Jason K Rivers
Oct 2, 2007·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Stanley R FullerDouglas Grossman
Sep 17, 2013·Metabolomics : Official Journal of the Metabolomic Society·T AbaffyR A DeFazio
Feb 4, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·V PiccoloG Argenziano
Oct 1, 2013·Dermatologic Clinics·Harald Kittler, Philipp Tschandl
Jun 19, 2012·Journal of the American Academy of Dermatology·Keith Duffy, Douglas Grossman
Sep 14, 2011·Current Problems in Cancer·Jennifer Nam ChoiDavid Leffell
May 10, 2011·Clinics in Laboratory Medicine·Philip D Da Forno, Gerald S Saldanha
May 17, 2011·Journal of the American Academy of Dermatology·Lena LyJohn William Kelly
Sep 1, 2009·Surgical Pathology Clinics·Philip D Da Forno, Gerald S Saldanha
Apr 25, 2009·Journal of the American Academy of Dermatology·Agnessa Gadeliya Goodson, Douglas Grossman
May 12, 2000·Mayo Clinic Proceedings·A J Bruce, D G Brodland
Apr 20, 2012·The Journal of Investigative Dermatology·Sieu L TranHelen Rizos
Aug 2, 2008·The Surgical Clinics of North America·Johan Hansson
Oct 6, 2007·The British Journal of Dermatology·P D Da FornoG S Saldanha
Jun 8, 2012·The Australasian Journal of Dermatology·Juber HafijiNigel P Burrows
Aug 19, 2015·CA: a Cancer Journal for Clinicians·Karen Colbert MaressoErnest T Hawk
Sep 1, 2004·Journal of the American Academy of Dermatology·Nancy E Thomas, Pamela Groben
Apr 6, 2004·Facial Plastic Surgery Clinics of North America·Christie Travelute Ammirati, George J Hruza
Nov 3, 2004·Facial Plastic Surgery Clinics of North America·Christie Travelute Ammirati, George J Hruza
Dec 20, 2014·Current Problems in Surgery·Alpin D Malkan, John A Sandoval
Dec 1, 1996·Journal of the American Academy of Dermatology·R Marks
Jan 1, 2005·Journal of the American Academy of Dermatology·Ingrid TylerAndreas Blum
Jan 25, 2014·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Tara BronsnickBabar K Rao
Jan 1, 2010·Cancers·William E DamskyMarcus Bosenberg
Apr 4, 2018·International Journal of Dermatology·David Alvarez MartinezRastine Merat
Feb 1, 2006·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·David E Elder
Jul 15, 2004·International Journal of Cancer. Journal International Du Cancer·Gerald SaldanhaJ Howard Pringle
Sep 23, 2014·American Journal of Clinical Pathology·Danielle ShitaraEdiléia Bagatin
Sep 22, 2010·Melanoma Research·Sherrie J Divito, Laura Korb Ferris
Mar 31, 2006·International Journal of Cancer. Journal International Du Cancer·Eva Y LeeDavid C Whiteman
Oct 12, 2019·The Australasian Journal of Dermatology·Massimiliano ScalvenziVincenzo Greco
Apr 10, 2014·Advances in Anatomic Pathology·Wolter J Mooi
Dec 1, 1992·Australian Journal of Public Health·R BorlandS Noy
Apr 3, 2020·Experimental & Molecular Medicine·Hyeongsun MoonAlexander D Borowsky
Oct 24, 2000·Clinical and Experimental Dermatology·R Marks
Feb 27, 2020·Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia·Riccardo PampenaCaterina Longo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Archives of Dermatology
Caroline BevonaHensin Tsao
The British Journal of Dermatology
S C WeatherheadC M Lawrence
Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
Stanley R FullerDouglas Grossman
International Journal of Dermatology
J B Howell
Seminars in Diagnostic Pathology
Deborah J Gersell
© 2021 Meta ULC. All rights reserved