Do annuloplasty rings designed to treat ischemic/functional mitral regurgitation alter left-ventricular dimensions in the acutely ischemic ovine heart?

The Journal of Thoracic and Cardiovascular Surgery
Wolfgang BotheD Craig Miller

Abstract

To quantify the effects of annuloplasty rings designed to treat ischemic/functional mitral regurgitation on left ventricular septal-lateral (S-L) and commissure-commissure (C-C) dimensions. Radiopaque markers were placed as opposing pairs on the S-L and C-C aspects of the mitral annulus and the basal, equatorial, and apical level of the left ventricle (LV) in 30 sheep. Ten true-sized Carpentier-Edwards Physio (PHY), Edwards IMR ETlogix (ETL), and GeoForm (GEO; all from Edwards Lifesciences, Irvine, Calif) annuloplasty rings were inserted in a releasable fashion. After 90 seconds of left circumflex artery occlusion with the ring implanted (RING), 4-dimensional marker coordinates were obtained using biplane videofluoroscopy. After ring release, another data set was acquired after another 90 seconds of left circumflex artery occlusion (NO RING). S-L and C-C diameters were computed as the distances between the respective marker pairs at end-diastole. Percent change in diameters was calculated between RING versus NO RING as 100 × (diameter in centimeters [RING] - diameter in centimeters [NO RING])/diameter in centimeters [NO RING]). Compared with NO RING, all ring types (PHY, ETL, and GEO) reduced mitral annular S-L dimensions by -2...Continue Reading

References

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Citations

Aug 8, 2020·Annals of Biomedical Engineering·Mrudang MathurManuel K Rausch
May 1, 2021·Biomedicines·Mattia VinciguerraErnesto Greco
Feb 17, 2019·The Journal of Thoracic and Cardiovascular Surgery·Manuel J Antunes
Feb 18, 2019·The Journal of Thoracic and Cardiovascular Surgery·Michele Di MauroAntonio M Calafiore

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