Do count-based differential expression methods perform poorly when genes are expressed in only one condition?

BioRxiv : the Preprint Server for Biology
Xiaobei Zhou, Mark D Robinson

Abstract

A response to Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data by Rapaport F, Khanin R, Liang Y, Pirun M, Krek A, Zumbo P, Mason CE, Socci ND and Betel D, Genome Biol 2013, 14:R95

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