Do early MRI signals predict lesion size in a neonatal stroke rat model?

AJNR. American Journal of Neuroradiology
Sebastien FauChristiane Charriaut-Marlangue

Abstract

In this study, we compared lesion size by using VADC and VT2 at 0, 2, 5, 24, and 48 hours and histologic lesions at 48 hours in a P7 rat stroke model. The best correlation between VHISTO and VADC was at H0, and between VHISTO and VT2, at H2-H5. Early MR imaging signals allowed excluding "no-lesion" and "no-reflow" animals to help standardize this neonatal stroke model and predict lesion size.

References

Jul 8, 2000·Stroke; a Journal of Cerebral Circulation·N DeruginZ S Vexler
Dec 15, 2006·Journal of Neurochemistry·Sylvain RenolleauChristiane Charriaut-Marlangue
Oct 24, 2007·Experimental Neurology·Sebastien FauChristiane Charriaut-Marlangue
Nov 6, 2007·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Gregory A LodygenskyJeffrey J Neil
Jan 21, 2010·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Tracy D Farr, Susanne Wegener
Mar 23, 2011·Journal of Neuroscience Methods·Philippe BonninSylvain Renolleau

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.