PMID: 8459058Apr 1, 1993Paper

Do false positive thallium-201 scans lead to unnecessary catheterization? Outcome of patients with perfusion defects on quantitative planar thallium-201 scintigraphy

Journal of the American College of Cardiology
R L DesmaraisG A Beller

Abstract

We postulated that artifactually abnormal thallium-201 scans are well identified at the time of initial clinical interpretation by experienced readers and do not lead to unnecessary coronary angiography. Exercise thallium-201 scintigraphy employing quantitative imaging techniques has yielded sensitivity and specificity values of 80% to 90%. There are image artifacts, such as breast shadows, and variants of normal that, if not correctly identified, can lead to a high false positive rate for detection of coronary artery disease. Data from 338 consecutive patients with one or more focal thallium-201 defects on quantitative planar images were reviewed. All patients had undergone symptom-limited exercise scintigraphy and were classified as having either artifactual or nonartifactual thallium-201 defects after review of clinical reports. Of the 265 patients with defects judged to be nonartifactual on clinical readings, 167 underwent coronary angiography, which demonstrated significant coronary artery disease (> or = 50% stenosis) in 161 (96%) and normal findings in 6. Four of the latter six had documented prior myocardial infarction. The remaining 73 patients (85% female) had thallium-201 defects deemed to be artifactual on clinical ...Continue Reading

References

Nov 1, 1990·Annals of Internal Medicine·T S Kotler, G A Diamond
Jan 1, 1985·Seminars in Nuclear Medicine·F J WackersJ P Clements
Mar 1, 1986·Journal of the American College of Cardiology·S KaulG M Pohost
Apr 1, 1985·The American Journal of Cardiology·F X PameliaG A Beller
Dec 1, 1984·Southern Medical Journal·L M PrisantA A Carr
Jul 1, 1984·Journal of the American College of Cardiology·T M BatemanD S Berman

❮ Previous
Next ❯

Citations

Dec 14, 2005·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Yasmin MasoodFrans J Th Wackers
Jan 11, 2003·The American Journal of Cardiology·George Allan Beller
May 1, 1995·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·T M BatemanR W Ligon
Jul 1, 1995·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·L L Johnson
Feb 10, 1998·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·F J Wackers
Jul 13, 2006·British Journal of Nursing : BJN·Louise A Danks
Jul 9, 2008·Journal of Cardiovascular Medicine·Joseph A DiamondMilena J Henzlova

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.