Do high participation rates improve effects of population-based general health checks?

Preventive Medicine
Anne Mette BenderCharlotta Pisinger

Abstract

The aim is to investigate if the effect of a health check differs between areas with different participation rates. The Inter99 population-based randomized lifestyle intervention study covered 73 areas within the suburbs of Copenhagen, Denmark. Adults aged 30-60years were randomly drawn from a population and were randomized to intervention group (n=11,483) or control group (n=47,122). Participation rates in the health check varied considerably between areas (mean 52%; range 35-85%). In separate survival analyses, area participation rate was included both as a continuous exposure variable and as a categorical variable (tertiles; low: 35-49%, meddle: 50-54%, high: 55-84%). All persons in the intervention and control group were followed in registers for 10-year total mortality and combined events (ischemic heart disease, stroke, or both). In adjusted models (including sociodemographic variables, ethnicity, number of children and comorbidity), among men, there was no difference in risk of death between areas with varying participation rates. Surprisingly, among women living in high-participation areas a significantly higher risk of all-cause mortality (HR: 1.32 [1.03-1.69]) was found in the intervention group (ref=controls). For bo...Continue Reading

References

Jan 1, 1986·Journal of Chronic Diseases·G D FriedmanB H Fireman
Dec 10, 2003·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Torben JørgensenCharlotta Pisinger
Mar 2, 2005·Journal of Advanced Nursing·Paul M GaldasPaul Marshall
Jan 21, 2011·The Cochrane Database of Systematic Reviews·Shah EbrahimGeorge Davey Smith
Aug 17, 2012·The Cochrane Database of Systematic Reviews·Diana DiaoFrancois Gueyffier
Sep 18, 2013·BMJ : British Medical Journal·Bruno HelenoJohn Brodersen
Feb 26, 2014·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Si SiNigel P Stocks
Oct 7, 2015·BMC Medical Research Methodology·Jennifer S MindellUNKNOWN HES Response Rate Group

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Citations

Dec 13, 2018·International Journal of Public Health·Anne Mette BenderCharlotta Pisinger
Jun 9, 2021·JAMA : the Journal of the American Medical Association·David T LissJeffrey A Linder

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