Do humans show velocity-storage in the vertical rVOR?

Progress in Brain Research
G BertoliniS Ramat

Abstract

To investigate the contribution of the vestibular velocity-storage mechanism (VSM) to the vertical rotational vestibulo-ocular reflex (rVOR) we recorded eye movements evoked by off-vertical axis rotation (OVAR) using whole-body constant-velocity pitch rotations about an earth-horizontal, interaural axis in four healthy human subjects. Subjects were tumbled forward, and backward, at 60 deg/s for over 1 min using a 3D turntable. Slow-phase velocity (SPV) responses were similar to the horizontal responses elicited by OVAR along the body longitudinal axis, ('barbecue' rotation), with exponentially decaying amplitudes and a residual, otolith-driven sinusoidal response with a bias. The time constants of the vertical SPV ranged from 6 to 9 s. These values are closer to those that reflect the dynamic properties of vestibular afferents than the typical 20 s produced by the VSM in the horizontal plane, confirming the relatively smaller contribution of the VSM to these vertical responses. Our preliminary results also agree with the idea that the VSM velocity response aligns with the direction of gravity. The horizontal and torsional eye velocity traces were also sinusoidally modulated by the change in gravity, but showed no exponential de...Continue Reading

Citations

May 9, 2012·Experimental Brain Research·Benjamin T Crane
Sep 5, 2012·Experimental Brain Research·Benjamin T Crane
Feb 26, 2016·Frontiers in Neurology·Giovanni Bertolini, Dominik Straumann
Sep 13, 2011·Acta Oto-laryngologica·Kayoko Higashi-ShingaiHidenori Inohara
Nov 27, 2014·Frontiers in Neurology·Susan KingRichard F Lewis
Dec 21, 2010·Experimental Brain Research·G Bertolini, S Ramat
May 11, 2016·Journal of Neurology·Kwang-Dong ChoiDavid S Zee
Dec 18, 2019·The Journal of Laryngology and Otology·F ComacchioM Mion

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