Do I know you? Examining face and object memory in frontotemporal dementia

Neuropsychologia
Fiona KumforO Piguet

Abstract

The ability to perceive, learn and recognise faces is a complex ability, which is key to successful social interactions. This ability is proposed to be coordinated by neural regions in the occipital and temporal lobes, specialised for face perception and memory. While previous studies have suggested that memory for faces is compromised in some dementia syndromes, it remains unclear whether this simply reflects more generalised memory deficits. Here, we examined basic face perception (Identity-Matching), face recognition (Cambridge Face Memory Task) and object recognition (Cambridge Car Memory Task) in 11 semantic dementia (SD) patients (8 left-lateralised, 3 right-lateralised) and 13 behavioural-variant frontotemporal dementia (bvFTD) patients, compared with 11 controls. On the Identity-Matching task, bvFTD were impaired compared to controls, with a similar trend observed in the SD group. Importantly, both bvFTD and SD also demonstrated impaired face recognition. In contrast, only bvFTD showed impaired object recognition, with SD performing within normal limits on this task. Voxel-based morphometry analyses revealed that Identity-Matching and face recognition were associated with partly dissociable regions including the fusifor...Continue Reading

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Citations

Jan 27, 2016·Brain : a Journal of Neurology·Fiona KumforOlivier Piguet
Jul 15, 2015·Neuropsychologia·Jan Van den StockMathieu Vandenbulcke
Feb 3, 2018·Brain : a Journal of Neurology·Fiona KumforOlivier Piguet
Feb 15, 2019·Neurology·Peter S PressmanKatherine P Rankin
Jan 30, 2020·Social Cognitive and Affective Neuroscience·Alice Y HuaRobert W Levenson
Feb 13, 2020·Current Opinion in Neurology·Olivier Piguet, Fiona Kumfor
Apr 5, 2018·Journal of Alzheimer's Disease : JAD·Maxime BertouxMichael Hornberger
Mar 6, 2018·Journal of Alzheimer's Disease : JAD·John R Hodges, Olivier Piguet
May 6, 2021·Journal of Clinical and Translational Science·Christina PresslJonathan N Tobin
Nov 20, 2021·Journal of Neurology·Maria Antonietta MagnoFederica Agosta

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