Do injury characteristics predict the severity of acute neuropsychological deficits following sports-related concussion? A meta-analysis

Journal of the International Neuropsychological Society : JINS
Brooke K DouganGina Geffen

Abstract

The utility of injury characteristics for predicting the severity of post-concussion outcomes remains equivocal. The purpose of this meta-analysis was to quantify the predictive relationship between these variables to inform classification of acute injury severity. Thirty-one empirical samples of concussed athletes, for which rates of loss of consciousness and/or amnesia were reported, were included in a meta-analysis evaluating acute outcomes following sports-related concussion. Outcome measures of interest were neuropsychological tests first administered 1-10 days post-injury. Loss of consciousness and anterograde amnesia significantly predicted more severe neuropsychological deficits within 10 days of concussion in studies using pre-injury baseline, but not control group, comparisons. Retrograde amnesia significantly predicted acute neuropsychological dysfunction (d = -1.03) irrespective of comparison group. Although small sample sizes require conservative interpretation and future replication, the evidence suggests that retrograde amnesia, rather than loss of consciousness, may be used to classify the acute severity of concussion.

References

Mar 1, 1975·Lancet·B Jennett, M Bond
Apr 1, 1990·Journal of Neurology, Neurosurgery, and Psychiatry·B E LeiningerE A Peck
Jun 1, 1997·Journal of Clinical and Experimental Neuropsychology·L M BinderG J Larrabee
Dec 11, 1999·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·M R LovellJ C Maroon
Oct 14, 2000·The American Journal of Sports Medicine·K M GuskiewiczW E Garrett
Jul 12, 2003·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Michael W CollinsJoseph Maroon
Nov 1, 2003·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·G L IversonS S Smith
Jan 9, 2004·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Michael McCreaKevin Guskiewicz
Nov 4, 2004·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Chad A AsplundCara H Olsen
Oct 8, 2005·Journal of the International Neuropsychological Society : JINS·Heather G Belanger, Rodney D Vanderploeg
Nov 23, 2006·Neurosurgical Focus·Elliot J PellmanUNKNOWN National Football League's Committee on Mild Traumatic Brain Injury
Nov 23, 2006·Neurosurgical Focus·Robert C CantuTamara C Valovich McLeod
Nov 23, 2006·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Dennis CaineNicola Maffulli
Dec 17, 2009·Journal of the International Neuropsychological Society : JINS·Heather G BelangerRodney D Vanderploeg
Dec 1, 1946·Brain : a Journal of Neurology·W R RUSSELL, P W NATHAN

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Citations

Aug 5, 2015·Journal of Clinical and Experimental Neuropsychology·Victoria C MerrittPeter A Arnett
Jun 2, 2017·British Journal of Sports Medicine·Grant L IversonGary S Solomon
Jul 6, 2016·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Alicia M SufrinkoAnthony P Kontos
Aug 11, 2020·Journal of the International Neuropsychological Society : JINS·Victoria C MerrittPeter A Arnett
Aug 23, 2020·Headache·Randolph W Evans, Adriana M Strutt
Nov 20, 2020·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Peltonen KatiHokkanen Laura
Sep 18, 2020·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Fionn BüttnerGrant L Iverson

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