Do Medications Commonly Prescribed to Patients with Peripheral Arterial Disease Have an Effect on Nutritional Status? A Review of the Literature

Annals of Vascular Surgery
Renee FentonMichelle D Miller

Abstract

Polypharmacy is common among patients with peripheral arterial disease (PAD) with a combination of medications used for risk-factor modification and medical management of the disease itself. Interaction between commonly prescribed medications and nutritional status has not previously been well described. This review aims to critically appraise evidence exploring associations between medications commonly prescribed to patients with PAD and nutritional status and provide recommendations for practice. A comprehensive literature search was conducted to locate studies relating to nutrient interactions among lipid-lowering, antihypertensive, antiplatelet, and oral hypoglycemic drug classes. Quality of the evidence was rated on the basis of recommendations by the National Health and Medical Research Council. A total of 25 articles were identified as suitable and included in the review. No studies were specific to patients with PAD, and hence findings highlighting risk of ubiquinone (coenzyme Q10 [CoQ10]) depletion with lipid-lowering medications, zinc depletion with antihypertensive medications, and vitamin B12 depletion with oral hypoglycemic medications are extrapolated from heterogeneous groups of patients and healthy adults. The b...Continue Reading

References

Nov 1, 1993·Journal of Clinical Pathology·G F WattsP J Quinn
Jul 4, 1997·Clinica Chimica Acta; International Journal of Clinical Chemistry·J A HumanH C Potgieter
Jan 1, 1997·Molecular Aspects of Medicine·S A MortensenM Rohde
Feb 27, 1998·Journal of the American College of Nutrition·A GolikJ Weissgarten
Feb 7, 2002·JAMA : the Journal of the American Medical Association·Antti JulaTapani Rönnemaa
Feb 25, 2003·The Journal of Cardiovascular Nursing·Barbara Sarter
Nov 18, 2004·AJR. American Journal of Roentgenology·Harald O StolbergIsabelle Trop
Dec 24, 2004·Current Opinion in Critical Care·Didier Dreyfuss
Oct 22, 2005·Journal of Clinical Pharmacology·Shuichi TsuruokaAkio Fujimura
Jul 29, 2006·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Heiner K BertholdIoanna Gouni-Berthold
Oct 13, 2006·Archives of Internal Medicine·Rose Zhao-Wei TingKai Ming Chow
Dec 5, 2006·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·L NorgrenKenneth Rosenfield
Jan 16, 2007·Journal of Vascular Surgery·L NorgrenUNKNOWN TASC II Working Group
Jan 25, 2007·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Alan B G LansdownMagnus S Agren
May 8, 2009·The American Journal of Clinical Nutrition·Nicola M LoweTamás Decsi
Jun 1, 2010·The Proceedings of the Nutrition Society·Pamela Mason
Mar 17, 2011·Angiology·Andrew W GardnerPolly S Montgomery
May 10, 2011·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·David CotánJosé A Sánchez-Alcázar
Jan 10, 2012·Age·Eugenio MocchegianiAscension Marcos
Jul 4, 2012·The Journal of Clinical Hypertension·Carly B RasmussenDeborah S Minor
Aug 10, 2012·BMJ : British Medical Journal·Jennifer LaydenUNKNOWN Guideline Development Group
Jan 30, 2013·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Eric T Stoopler, Arthur S Kuperstein
Mar 8, 2013·Nutrition·Dimitrios SamarasClaude Pichard
Mar 29, 2013·BMJ Case Reports·John Ross Crawford, Daphne Say
Jan 7, 2014·Frontiers in Bioscience (Landmark Edition)·Juan Garrido-MaraverJose A Sanchez-Alcazar
Feb 22, 2014·Vascular Medicine·Laura Brook-BarclayJames I Spark

❮ Previous
Next ❯

Citations

Oct 11, 2017·Current Opinion in Clinical Nutrition and Metabolic Care·Milta O Little
Nov 26, 2019·The American Journal of Clinical Nutrition·Jim Kaput
May 31, 2019·Nutrients·Christopher L DelaneyMichelle D Miller
Jul 3, 2021·Antioxidants·Francisco M Gutierrez-MariscalJosé López-Miranda

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Related Papers

Circulation
Hsin-Chia HungKaumudi J Joshipura
European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
Peripheral Arterial Diseases Antiplatelet Consensus Group
Progress in Cardiovascular Diseases
Sanjay GandhiMichael R Jaff
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
E Myhre, P F Hjort
Journal of Cardiovascular Pharmacology and Therapeutics
Stella S DaskalopoulouDimitri P Mikhailidis
© 2021 Meta ULC. All rights reserved